ToxHistory

Bimekizumab, a Novel Humanized IgG1 Antibody That Neutralizes Each IL-17A and IL-17F

• Interleukin (IL)-17A is a key driver of irritation and the principal goal of anti-IL-17 therapeutic monoclonal antibodies. IL-17A, and its structurally related member of the family IL-17F, have been proven to be functionally dysregulated in sure human immune-mediated inflammatory ailments comparable to psoriasis, psoriatic arthritis, and axial spondyloarthritis. Given the overlapping biology of those two cytokines, we postulated that twin neutralization of IL-17A and IL-17F could present a larger depth of medical response in IL-17-mediated ailments than IL-17A inhibition alone.
• We recognized 496.g1, a humanized antibody with sturdy affinity for IL-17A however poor affinity for IL-17F. Affinity maturation of 496.g1 to 496.g3 drastically enhanced the affinity of the Fab fragment for IL-17F whereas retaining sturdy binding to IL-17A. As an IgG1, the affinity for IL-17A and IL-17F was 3.2 pM and 23 pM, respectively.
• Comparability of 496.g3 IgG1 with the commercially accessible anti-IL-17A monoclonal antibodies ixekizumab and secukinumab, by floor plasmon resonance and in a human in vitroIL-17A practical assay, confirmed that 496.g3 and ixekizumab show equal affinity for IL-17A, and that each antibodies are markedly stronger than secukinumab. In distinction to ixekizumab and secukinumab, 496.g3 exhibited the distinctive function of additionally with the ability to neutralize the organic exercise of IL-17F.
• Due to this fact, antibody 496.g3 was chosen for medical growth for its potential to neutralize the biologic perform of each IL-17A and IL-17F and was renamed bimekizumab (previously UCB4940). Early medical information in sufferers with psoriasis, in these with psoriatic arthritis, and from the Section 2 research in psoriasis, psoriatic arthritis, and ankylosing spondylitis, are encouraging and assist the focused method of twin neutralization of IL-17A and IL-17F. Taken collectively, these findings present the rationale for the continued medical analysis of bimekizumab in sufferers with immune-mediated inflammatory ailments.

 

Mouse LIF
MBS691665-5x005mg	MyBiosource	5x0.05mg	EUR 2045

Mouse LIF
MBS692107-001mg	MyBiosource	0.01mg	EUR 305

Mouse LIF
MBS692107-5x001mg	MyBiosource	5x0.01mg	EUR 1080

LIF，Mouse
E34M066M	EnoGene	5 μg	EUR 155

LIF, Mouse
HY-P7084	MedChemExpress	50ug	EUR 639.6

LIF, mouse
MO16102	Neuromics	100 ug	EUR 810

LIF, Mouse
MBS8575391-0005mg	MyBiosource	0.005mg	EUR 245

LIF, Mouse
MBS8575391-5x0005mg	MyBiosource	5x0.005mg	EUR 940

Mouse Anti-Human LIF Monoclonal Antibody
MBS592457-01mg	MyBiosource	0.1mg	EUR 365

Mouse Anti-Human LIF Monoclonal Antibody
MBS592457-05mg	MyBiosource	0.5mg	EUR 530

Mouse Anti-Human LIF Monoclonal Antibody
MBS592457-5x05mg	MyBiosource	5x0.5mg	EUR 2140

Mouse Anti-Human LIF Monoclonal Antibody
MBS592458-01mg	MyBiosource	0.1mg	EUR 365

Mouse Anti-Human LIF Monoclonal Antibody
MBS592458-05mg	MyBiosource	0.5mg	EUR 530

Mouse Anti-Human LIF Monoclonal Antibody
MBS592458-5x05mg	MyBiosource	5x0.5mg	EUR 2140

Mouse Anti-Human LIF Monoclonal Antibody
MBS592459-01mg	MyBiosource	0.1mg	EUR 365

Mouse Anti-Human LIF Monoclonal Antibody
MBS592459-05mg	MyBiosource	0.5mg	EUR 530

Mouse Anti-Human LIF Monoclonal Antibody
MBS592459-5x05mg	MyBiosource	5x0.5mg	EUR 2140

Mouse LIF Protein
E40MOP1672	EnoGene	20ug	EUR 495

Mouse LIF Protein
E40MOP2026	EnoGene	20ug	EUR 495

Mouse LIF Protein
E40MOP2028	EnoGene	20ug	EUR 495

LIF, Mouse, Monoclonal Antibody, Mouse
MBS555093-01mg	MyBiosource	0.1mg	EUR 745

LIF, Mouse, Monoclonal Antibody, Mouse
MBS555093-5x01mg	MyBiosource	5x0.1mg	EUR 3210

LIF siRNA (Mouse)
MBS8224619-15nmol	MyBiosource	15nmol	EUR 405

LIF siRNA (Mouse)
MBS8224619-30nmol	MyBiosource	30nmol	EUR 565

LIF siRNA (Mouse)
MBS8224619-5x30nmol	MyBiosource	5x30nmol	EUR 2450

Recombinant Mouse LIF
Z200195	ABM	10 µg	EUR 85
Description: LIF is a multifunctional secreted glycoprotein that exists in both soluble and matrix-bound forms. It displays biologic activities ranging from the differentiation of myeloid leukemic cells into macrophage lineage to effects on bone metabolism, inflammation, neural development, embryogenesis, and the maintenance of implantation. It is now clear that LIF is related in both structure and mechanism of action to the interleukin IL-6 family of cytokines, which also includes IL-11, ciliary neurotrophic factor, oncostatin M, and cardiotrophin 1. The actions of these cytokines are mediated through specific cell-surface receptors that consist of a unique chain and the shared signal transducing subunit gp130.

Recombinant Mouse LIF
Z200197	ABM	100 µg	EUR 385
Description: LIF is a multifunctional secreted glycoprotein that exists in both soluble and matrix-bound forms. It displays biologic activities ranging from the differentiation of myeloid leukemic cells into macrophage lineage to effects on bone metabolism, inflammation, neural development, embryogenesis, and the maintenance of implantation. It is now clear that LIF is related in both structure and mechanism of action to the interleukin IL-6 family of cytokines, which also includes IL-11, ciliary neurotrophic factor, oncostatin M, and cardiotrophin 1. The actions of these cytokines are mediated through specific cell-surface receptors that consist of a unique chain and the shared signal transducing subunit gp130.

Recombinant Mouse LIF
Z200199	ABM	1.0 mg	EUR 1200
Description: LIF is a multifunctional secreted glycoprotein that exists in both soluble and matrix-bound forms. It displays biologic activities ranging from the differentiation of myeloid leukemic cells into macrophage lineage to effects on bone metabolism, inflammation, neural development, embryogenesis, and the maintenance of implantation (2). It is now clear that LIF is related in both structure and mechanism of action to the interleukin IL-6 family of cytokines, which also includes IL-11, ciliary neurotrophic factor, oncostatin M, and cardiotrophin 1 (2). The actions of these cytokines are mediated through specific cell-surface receptors that consist of a unique chain and the shared signal transducing subunit gp130.

Recombinant Mouse LIF
Z200485	ABM	100 µg	EUR 1500
Description: LIF is a multifunctional secreted glycoprotein that exists in both soluble and matrix-bound forms. It displays biologic activities ranging from the differentiation of myeloid leukemic cells into macrophage lineage to effects on bone metabolism, inflammation, neural development, embryogenesis, and the maintenance of implantation (2). It is now clear that LIF is related in both structure and mechanism of action to the interleukin IL-6 family of cytokines, which also includes IL-11, ciliary neurotrophic factor, oncostatin M, and cardiotrophin 1 (2). The actions of these cytokines are mediated through specific cell-surface receptors that consist of a unique chain and the shared signal transducing subunit gp130.

Recombinant Mouse LIF
MBS7609292-005mg	MyBiosource	0.05mg	EUR 405

Recombinant Mouse LIF
MBS7609292-02mg	MyBiosource	0.2mg	EUR 760

Recombinant Mouse LIF
MBS7609292-1mg	MyBiosource	1mg	EUR 2175

Recombinant Mouse LIF
MBS7609292-5x1mg	MyBiosource	5x1mg	EUR 8410

Recombinant Mouse LIF
MBS4159936-001mg	MyBiosource	0.01mg	EUR 230

Recombinant Mouse LIF
MBS4159936-01mg	MyBiosource	0.1mg	EUR 560

Recombinant Mouse LIF
MBS4159936-1mg	MyBiosource	1mg	EUR 1500

Recombinant Mouse LIF
MBS4159936-5x1mg	MyBiosource	5x1mg	EUR 6500

Recombinant Mouse LIF
P1174-.005	ApexBio	5ug	EUR 108.8
Description: Peptides & Proteins|Recombinant Proteins

Recombinant Mouse LIF
P1174-.1	ApexBio	100ug	EUR 840.8
Description: Peptides & Proteins|Recombinant Proteins

Recombinant Mouse LIF
P1174-.5	ApexBio	500ug	EUR 1885.6
Description: Peptides & Proteins|Recombinant Proteins

Anti-Mouse LIF Antibody
103-M263	ReliaTech	100 µg	EUR 399
Description: Based on its helical structure, LIF (Leukemia Inhibitory Factor) is considered a member of the Interleukin-6 family of cytokines. Functionally, it has been implicated in a many physiological processes including development, hematopoiesis, bone metabolism, and inflammation. Some cell types known to express LIF include activated T cells, monocytes, astrocytes, osteoblasts, keratinocytes, regenerating skeletal muscle, mast cells, and fibroblasts.

Anti-Mouse LIF Antibody
103-PA05S	ReliaTech	100 µg	EUR 126
Description: Leukemia Inhibitory Factor also called LIF is a lymphoid factor that promotes long-term maintenance of embryonic stem cells by suppressing spontaneous differentiation. Leukemia Inhibitory Factor has several functions such as cholinergic neuron differentiation, control of stem cell pluripotency, bone & fat metabolism, mitogenesis of factor dependent cell lines & promotion of megakaryocyte production in vivo. Human and mouse LIF exhibit a 78% identity in its amino acid sequence. Human LIF is as active on human cells as is it is on mouse cells, though mouse LIF is about 1000 fold less active on human cells, than human LIF.

Rabbit Anti-Mouse LIF
103-PA05	Angio Proteomie	100ug	EUR 240

LIF (mouse), (recombinant)
MBS566073-1mL	MyBiosource	1mL	EUR 1470

LIF (mouse), (recombinant)
MBS566073-5x1mL	MyBiosource	5x1mL	EUR 6555

Mouse LIF ELISA Kit
E28L0650	EnoGene	96T	EUR 666.67

Mouse LIF ELISA Kit
EK5250	SAB	96 tests	EUR 599

Mouse Lif ELISA Kit
EF012949	Nova Lifetech	96tests	EUR 566

Mouse LIF ELISA Kit
EML0014	Abclonal	96Tests	EUR 625.2

Mouse LIF shRNA Plasmid
20-abx971321	Abbexa	Ask for price Ask for price	150 µg 300 µg

LIF, Human, Monoclonal Antibody, Mouse
MBS555094-01mg	MyBiosource	0.1mg	EUR 745

LIF, Human, Monoclonal Antibody, Mouse
MBS555094-5x01mg	MyBiosource	5x0.1mg	EUR 3210

Recombinant Mouse LIF protein
IMP-1308	Creative BioMart	10µg	EUR 360
Description: Recombinant Proteins

Mouse LIF Recombinant Protein
M30-007	ReliaTech	10 µg	EUR 99.75
Description: Leukemia Inhibitory Factor also called LIF is a lymphoid factor that promotes long-term maintenance of embryonic stem cells by suppressing spontaneous differentiation. Leukemia Inhibitory Factor has several functions such as cholinergic neuron differentiation, control of stem cell pluripotency, bone & fat metabolism, mitogenesis of factor dependent cell lines & promotion of megakaryocyte production in vivo. Human and mouse LIF exhibit a 78% identity in its amino acid sequence. Human LIF is as active on human cells as is it is on mouse cells, though mouse LIF is about 1000 fold less active on human cells, than human LIF. Recombinant mouse LIF produced in E. coli is a single, non-glycosylated, polypeptide chain containing 180 amino acids and having a molecular mass of 19.86 kDa.

Mouse LIF Recombinant Protein
M30-008	ReliaTech	50 µg	EUR 246.75
Description: Leukemia Inhibitory Factor also called LIF is a lymphoid factor that promotes long-term maintenance of embryonic stem cells by suppressing spontaneous differentiation. Leukemia Inhibitory Factor has several functions such as cholinergic neuron differentiation, control of stem cell pluripotency, bone & fat metabolism, mitogenesis of factor dependent cell lines & promotion of megakaryocyte production in vivo. Human and mouse LIF exhibit a 78% identity in its amino acid sequence. Human LIF is as active on human cells as is it is on mouse cells, though mouse LIF is about 1000 fold less active on human cells, than human LIF. Recombinant mouse LIF produced in E. coli is a single, non-glycosylated, polypeptide chain containing 180 amino acids and having a molecular mass of 19.86 kDa.

Recombinant Mouse LIF Protein
R01400-1	BosterBio	100ug/vial	EUR 352.8

Recombinant Mouse LIF protein
CD00323-5ug	Jiaxing Korain Biotech Ltd (BT Labs)	5ug	EUR 176
Description: Leukemia inhibitory factor (LIF) is a member of Interleukin 6 family. This protein is mainly expressed in the trophectoderm of the developing embryo, with its receptor LIFR expressed throughout the inner cell mass. LIF has the capacity to induce terminal differentiation in leukemic cells. Its activities include the induction of hematopoietic differentiation in normal and myeloid leukemia cells, the induction of neuronal cell differentiation, and the stimulation of acute-phase protein synthesis in hepatocytes. LIF is used in mouse embryonic stem cell culture, because that removal of LIF pushes stem cells toward differentiation, but they retain their proliferative potential or pluripotency. It is also used in phase II clinical trial, which can assist embryo implantation in women who have failed to become pregnant despite assisted reproductive technologies (ART). Mature mouse LIF shares 78 % a.a. sequence identity with Human LIF.

Recombinant Mouse LIF Protein
PKSM041100-100ug	Elabscience Biotech	100ug	EUR 739
Description: Mouse

Recombinant Mouse LIF Protein
PKSM041100-20ug	Elabscience Biotech	20ug	EUR 249
Description: Mouse

Recombinant Mouse LIF Protein
MBS8249390-001mg	MyBiosource	0.01mg	EUR 230

Recombinant Mouse LIF Protein
MBS8249390-005mg	MyBiosource	0.05mg	EUR 480

Recombinant Mouse LIF Protein
MBS8249390-05mg	MyBiosource	0.5mg	EUR 2825

Recombinant Mouse LIF Protein
MBS8249390-5x05mg	MyBiosource	5x0.5mg	EUR 12640

Recombinant Mouse LIF Protein
MBS1751002-01mg	MyBiosource	0.1mg	EUR 315

Recombinant Mouse LIF Protein
MBS1751002-5x01mg	MyBiosource	5x0.1mg	EUR 1270

Rat Monoclonal anti-mouse LIF
mAP-0122	Angio Proteomie	100ug	EUR 250

Sheep Polyclonal anti-mouse LIF
mAP-5260	Angio Proteomie	50ug	EUR 400

Anti-LIF Antibody, Mouse Monoclonal
MBS8107490-01mL	MyBiosource	0.1mL	EUR 300

Anti-LIF Antibody, Mouse Monoclonal
MBS8107490-5x01mL	MyBiosource	5x0.1mL	EUR 1200

anti- LIF antibody
LSMab09804	Nova Lifetech	100ug	EUR 275

anti- LIF antibody
FNab09804	FN Test	100µg	EUR 658.5
Description: Antibody raised against LIF

Mouse LIF PicoKine ELISA Kit
EK0580	BosterBio	96 wells	EUR 510
Description: For quantitative detection of mouse LIF in cell culture supernates, serum and plasma (heparin, EDTA).

Mouse LIF PicoKine ELISA Kit
MBS178717-5x96StripWells	MyBiosource	5x96-Strip-Wells	EUR 2755

Mouse LIF PicoKine ELISA Kit
MBS178717-96StripWells	MyBiosource	96-Strip-Wells	EUR 600

LIF mouse monoclonal antibody, clone 4F7.2
MO16101-100	Origene Technologies GmbH	100 µg	Ask for price

LIF mouse monoclonal antibody, clone 2H2.2
MO16102-100	Origene Technologies GmbH	100 µg	Ask for price

Recombinant Mouse LIF, Tag Free
PM2019-.01	ApexBio	10ug	EUR 208
Description: Peptides & Proteins|Recombinant Proteins

Recombinant Mouse LIF, Tag Free
PM2019-.1	ApexBio	10X10ug	EUR 784
Description: Peptides & Proteins|Recombinant Proteins

Lif ORF Vector (Mouse) (pORF)
ORF049145	ABM	1.0 ug DNA	EUR 607.2

Lif ORF Vector (Mouse) (pORF)
ORF049146	ABM	1.0 ug DNA	EUR 607.2

LIF ELISA Kit (Mouse) (OKBB00760)
OKBB00760	Aviva Systems Biology	96 Wells	EUR 606
Description: Description of target: Leukemia inhibitory factor, or LIF, is an interleukin 6 class cytokine that affects cell growth by inhibiting differentiation. When LIF levels drop, the cells differentiate. The LIF was mapped gene to 22q11-q12.2 by Southern analysis of a series of mouse/human somatic cell hybrids and by in situ hybridization to the chromosomes of 2 normal males and some individuals with chromosomal rearrangements. The gene maps between the Philadelphia translocation BCR1 and the breakpoint of the translocation in cell line GM2324 at 22q12.2. LIF derives its name from its ability to induce the terminal differentiation of myeloid leukemic cells, thus preventing their continued growth. Other properties attributed to the cytokine include: the growth promotion and cell differentiation of different types of target cells, influence on bone metabolism, cachexia, neural development, embryogenesis and inflammation.;Species reactivity: Mouse;Application: ELISA;Assay info: ;Sensitivity: <10pg/ml

LIF, Mouse Recombinant , 1MIU/ml
L4500-001	GenDepot	1ml	EUR 406.8

LIF, Mouse Recombinant , 1MIU/ml
L4500-005	GenDepot	5x1ml	EUR 1431.6

LIF ELISA Kit (Mouse) (OKEH04045)
OKEH04045	Aviva Systems Biology	96 Wells	EUR 652.8
Description: Description of target: LIF has the capacity to induce terminal differentiation in leukemic cells. Its activities include the induction of hematopoietic differentiation in normal and myeloid leukemia cells, the induction of neuronal cell differentiation, and the stimulation of acute-phase protein synthesis in hepatocytes.;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.039 ng/mL

LIF, Mouse Recombinant , 10MIU/ml
L4501-001	GenDepot	1ml	EUR 1744.8

Mouse LIF HEK293 Overexpression Lysate
MBS8119752-03mg	MyBiosource	0.3mg	EUR 280

Mouse LIF HEK293 Overexpression Lysate
MBS8119752-5x03mg	MyBiosource	5x0.3mg	EUR 1205

Mouse LIF HEK293 Overexpression Lysate
MBS8119753-03mg	MyBiosource	0.3mg	EUR 280

Mouse LIF HEK293 Overexpression Lysate
MBS8119753-5x03mg	MyBiosource	5x0.3mg	EUR 1205

Purified recombinant Mouse LIF protein
MBS5308803-001mg	MyBiosource	0.01mg	EUR 550

Purified recombinant Mouse LIF protein
MBS5308803-5x001mg	MyBiosource	5x0.01mg	EUR 2435

LIFR, Recombinant, Mouse (Leukemia Inhibitory Factor Receptor, LIF Receptor, LIF-R, D-factor/LIF Receptor, CD118)
MBS636029-005mg	MyBiosource	0.05mg	EUR 800

LIFR, Recombinant, Mouse (Leukemia Inhibitory Factor Receptor, LIF Receptor, LIF-R, D-factor/LIF Receptor, CD118)
MBS636029-5x005mg	MyBiosource	5x0.05mg	EUR 3455

Mouse LIF Recombinant Protein Lyophilized
IMSLIFRLY5UG	Innovative research	each	EUR 317
Description: Mouse LIF Recombinant Protein Lyophilized

Mouse LIF Recombinant Protein Lyophilized
MBS8434242-INQUIRE	MyBiosource	INQUIRE	Ask for price

Nori® Mouse LIF ELISA Kit
GR117058	Genorise Scientific	96-well	EUR 461

Human CellExp? LIF, mouse recombinant
7268-10	Biovision	each	EUR 444

Leukemia Inhibitory Factor (LIF), mouse
PR16102	Neuromics	5 ug	EUR 522

Leukemia Inhibitory Factor (LIF), mouse
PR16102-B	Neuromics	each	EUR 436.5

Leukemia Inhibitory Factor (LIF), Mouse
MBS555550-0005mg	MyBiosource	0.005mg	EUR 500

Leukemia Inhibitory Factor (LIF), Mouse
MBS555550-001mg	MyBiosource	0.01mg	EUR 670

Leukemia Inhibitory Factor (LIF), Mouse
MBS555550-5x001mg	MyBiosource	5x0.01mg	EUR 2855

Mouse LIF protein, C-His tag
PRP1126-100ug	Abbkine	100 μg	EUR 379
Description: Mouse LIF protein, C-His tag, expressed in E. coli

Mouse LIF protein, C-His tag
PRP1126-1mg	Abbkine	1 mg	EUR 2509
Description: Mouse LIF protein, C-His tag, expressed in E. coli

Mouse LIF protein, C-His tag
PRP1126-20ug	Abbkine	20 μg	EUR 149
Description: Mouse LIF protein, C-His tag, expressed in E. coli

Mouse LIF protein, C-His tag
PRP1126-5ug	Abbkine	5 μg	EUR 59
Description: Mouse LIF protein, C-His tag, expressed in E. coli

Mouse LIF protein, C-His tag
MBS9719051-0005mg	MyBiosource	0.005mg	EUR 115

Mouse LIF protein, C-His tag
MBS9719051-002mg	MyBiosource	0.02mg	EUR 165

Mouse LIF protein, C-His tag
MBS9719051-01mg	MyBiosource	0.1mg	EUR 295

Mouse LIF protein, C-His tag
MBS9719051-1mg	MyBiosource	1mg	EUR 1680

Mouse LIF protein, C-His tag
MBS9719051-5x1mg	MyBiosource	5x1mg	EUR 7520

Lif (untagged) - Mouse leukemia inhibitory factor (Lif), transcript variant 1, (10ug)
MC208887	Origene Technologies GmbH	10 µg	Ask for price

Lif (untagged) - Mouse leukemia inhibitory factor (Lif), transcript variant 2, (10ug)
MC208888	Origene Technologies GmbH	10 µg	Ask for price

Recombinant Mouse Lif Protein, No Tag
E40MOP2217	EnoGene	20ug	EUR 495

Anti-Human LIF Antibody
101-M553	ReliaTech	100 µg	EUR 399
Description: Based on its helical structure, LIF (Leukemia Inhibitory Factor) is considered a member of the Interleukin-6 family of cytokines. Functionally, it has been implicated in a many physiological processes including development, hematopoiesis, bone metabolism, and inflammation. Some cell types known to express LIF include activated T cells, monocytes, astrocytes, osteoblasts, keratinocytes, regenerating skeletal muscle, mast cells, and fibroblasts.

Anti-Human LIF Antibody
102-PA05S	ReliaTech	100 µg	EUR 126
Description: Leukemia Inhibitory Factor also called LIF is a lymphoid factor that promotes long-term maintenance of embryonic stem cells by suppressing spontaneous differentiation. Leukemia Inhibitory Factor has several functions such as cholinergic neuron differentiation, control of stem cell pluripotency, bone & fat metabolism, mitogenesis of factor dependent cell lines & promotion of megakaryocyte production in vivo. Human and mouse LIF exhibit a 78% identity in its amino acid sequence. Human LIF is as active on human cells as is it is on mouse cells, though mouse LIF is about 1000 fold less active on human cells, than human LIF.

Rabbit Anti-Human LIF
102-PA05	Angio Proteomie	100ug	EUR 240

Lif (GFP-tagged) - Mouse leukemia inhibitory factor (Lif) transcript variant 1, (10ug)
MG223120	Origene Technologies GmbH	10 µg	Ask for price

Lif (GFP-tagged) - Mouse leukemia inhibitory factor (Lif) transcript variant 2, (10ug)
MG223901	Origene Technologies GmbH	10 µg	Ask for price

OKBB00760-96W - LIF ELISA Kit (Mouse)
OKBB00760-96W	Aviva Systems Biology	96wells	EUR 538

OKEH04045-96W - LIF ELISA Kit (Mouse)
OKEH04045-96W	Aviva Systems Biology	96Wells	EUR 425

Recombinant Mouse Lif Protein, low endotoxin
EPLE-19M	Creative BioMart	10ug	EUR 263.2
Description: Mouse

Lif (Myc-DDK-tagged) - Mouse leukemia inhibitory factor (Lif), transcript variant 1
MR223120	Origene Technologies GmbH	10 µg	Ask for price

Lif (Myc-DDK-tagged) - Mouse leukemia inhibitory factor (Lif), transcript variant 2
MR223901	Origene Technologies GmbH	10 µg	Ask for price

LIF Protein, Mouse, Recombinant (His Tag)
MBS8118864-01mg	MyBiosource	0.1mg	EUR 615

LIF Protein, Mouse, Recombinant (His Tag)
MBS8118864-1mg	MyBiosource	1mg	EUR 2530

LIF Protein, Mouse, Recombinant (His Tag)
MBS8118864-5x1mg	MyBiosource	5x1mg	EUR 11240

Leukemia Inhibitory Factor, Recombinant, Mouse (LIF, Differentiation-stimulating Factor, D Factor, Lif)
MBS635712-0005mg	MyBiosource	0.005mg	EUR 665

Leukemia Inhibitory Factor, Recombinant, Mouse (LIF, Differentiation-stimulating Factor, D Factor, Lif)
MBS635712-5x0005mg	MyBiosource	5x0.005mg	EUR 2845

Lif sgRNA CRISPR Lentivector set (Mouse)
K3872501	ABM	3 x 1.0 ug	EUR 406.8

Leukemia Inhibitory Factor (LIF) Polyclonal Antibody (Mouse)
4-PAA085Mu01	Cloud-Clone	Ask for price Ask for price Ask for price Ask for price Ask for price	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Mouse Leukemia Inhibitory Factor (LIF)

LIF, Leukemia inhibitory factor, murine (mouse)
RC234-18	Bio Basic	5ug	EUR 125.26

Sunlong Medical™ Mouse LIF ELISA Kit
EL0100Mo-48T	Sunlong	48T	EUR 398

Sunlong Medical™ Mouse LIF ELISA Kit
EL0100Mo-96T	Sunlong	96T	EUR 569

Mouse Leukemia Inhibitory Factor (LIF) Protein
20-abx067761	Abbexa	Ask for price Ask for price Ask for price Ask for price Ask for price	100 ug 10 ug 1 mg 200 ug 50 ug

Mouse Leukemia Inhibitory Factor (LIF) Protein
abx262959-1mg	Abbexa	1 mg	EUR 3801.6

Mouse Leukemia Inhibitory Factor (LIF) Protein
abx262959-3x10g	Abbexa	3x10 µg	EUR 393.6

Mouse Leukemia Inhibitory Factor (LIF) Protein
abx262959-3x2g	Abbexa	3x2 µg	EUR 276

Mouse Leukemia Inhibitory Factor (LIF) Protein
abx067761-100g	Abbexa	100 µg	EUR 550

Mouse Leukemia Inhibitory Factor (LIF) Protein
abx262959-10mg	Abbexa	10 mg	EUR 325

Mouse Leukemia Inhibitory Factor (LIF) Protein
abx262959-25mg	Abbexa	25 mg	EUR 3287.5

Mouse Leukemia Inhibitory Factor (LIF) Protein
abx262959-5mg	Abbexa	5 mg	EUR 225

Mouse Leukemia Inhibitory Factor (LIF) Protein
abx067761-10g	Abbexa	10 µg	EUR 212.5

Mouse Leukemia Inhibitory Factor (LIF) Protein
abx067761-50g	Abbexa	50 µg	EUR 387.5

Mouse LIF Flow Cytometry Assay - Group 3
MX85121	Antigenix America	96 Tests	EUR 270

Mouse LIF Protein, His Tag (MALS verified)
LIF-M5227	ACROBIOSYSTEMS	1mg	EUR 321
Description: Mouse LIF, His Tag (LIF-M5227) is expressed from human 293 cells (HEK293). It contains AA Ser 24 - Phe 203 (Accession # P09056-1).

Mouse LIF Protein, Tag Free (MALS verified)
LIF-M5219	ACROBIOSYSTEMS	20ug	EUR 2856.9
Description: Mouse LIF Protein, Tag Free (LIF-M5219) is expressed from human 293 cells (HEK293). It contains AA Ser 24 - Phe 203 (Accession # P09056-1).

Recombinant Mouse Leukemia Inhibitory Factor/lIF
AP75318	SAB	1mg	EUR 3209

Recombinant Mouse Leukemia Inhibitory Factor/lIF
C690-10ug	Novoprotein	10ug	EUR 175.2
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.

Recombinant Mouse Leukemia Inhibitory Factor/lIF
C690-1mg	Novoprotein	1mg	EUR 2739.6
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.

Recombinant Mouse Leukemia Inhibitory Factor/lIF
C690-500ug	Novoprotein	500ug	EUR 1935.6
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.

Recombinant Mouse Leukemia Inhibitory Factor/lIF
C690-50ug	Novoprotein	50ug	EUR 363.6
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.

Recombinant Mouse Leukemia inhibitory factor (Lif)
MBS951573-002mgBaculovirus	MyBiosource	0.02mg(Baculovirus)	EUR 1100

Recombinant Mouse Leukemia inhibitory factor (Lif)
MBS951573-002mgEColi	MyBiosource	0.02mg(E-Coli)	EUR 695

Recombinant Mouse Leukemia inhibitory factor (Lif)
MBS951573-002mgYeast	MyBiosource	0.02mg(Yeast)	EUR 855

Recombinant Mouse Leukemia inhibitory factor (Lif)
MBS951573-01mgEColi	MyBiosource	0.1mg(E-Coli)	EUR 810

Recombinant Mouse Leukemia inhibitory factor (Lif)
MBS951573-01mgYeast	MyBiosource	0.1mg(Yeast)	EUR 1000

LIF Protein Vector (Mouse) (pPM-C-HA)
PV196580	ABM	500 ng	EUR 723.6

LIF Protein Vector (Mouse) (pPM-C-HA)
PV196584	ABM	500 ng	EUR 723.6

Mouse LIF -Leukemia Inhibitory Factor- CLIA Kit
E-CL-M0038-24Tests	Elabscience Biotech	24 Tests	EUR 180
Description: Sandwich

Mouse LIF -Leukemia Inhibitory Factor- CLIA Kit
E-CL-M0038-48Tests	Elabscience Biotech	48 Tests	EUR 546
Description: Sandwich

Mouse LIF -Leukemia Inhibitory Factor- CLIA Kit
E-CL-M0038-96Tests	Elabscience Biotech	96 Tests	EUR 682
Description: Sandwich

Mouse LIF -Leukemia Inhibitory Factor- CLIA Kit
E-CL-M0038-96Tests10	Elabscience Biotech	96 Tests *10	EUR 6820
Description: Sandwich

Mouse LIF -Leukemia Inhibitory Factor- CLIA Kit
E-CL-M0038-96Tests5	Elabscience Biotech	96 Tests *5	EUR 3410
Description: Sandwich

Mouse LIF (Leukemia Inhibitory Factor) CLIA Kit
MBS2531217-5x96Tests	MyBiosource	5x96Tests	EUR 2565

Mouse LIF (Leukemia Inhibitory Factor) CLIA Kit
MBS2531217-96Tests	MyBiosource	96Tests	EUR 560

LIF Protein Vector (Mouse) (pPB-C-His)
PV196578	ABM	500 ng	EUR 723.6

LIF Protein Vector (Mouse) (pPB-N-His)
PV196579	ABM	500 ng	EUR 723.6

LIF Protein Vector (Mouse) (pPM-C-His)
PV196581	ABM	500 ng	EUR 723.6

LIF Protein Vector (Mouse) (pPB-C-His)
PV196582	ABM	500 ng	EUR 723.6

LIF Protein Vector (Mouse) (pPB-N-His)
PV196583	ABM	500 ng	EUR 723.6

LIF Protein Vector (Mouse) (pPM-C-His)
PV196585	ABM	500 ng	EUR 723.6

Mouse Lif/ Leukemia inhibitory factor ELISA Kit
E1656Mo	Sunlong	1 Kit	EUR 543
Description: Differentiation-stimulating factor,D factor

Mouse Lif / Leukemia inhibitory factor ELISA Kit
E0085m	EIAab	96T	EUR 776

Mouse Lif(Leukemia inhibitory factor) ELISA Kit
EM0237	FN Test	96T	EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 46.9pg/ml

 

Myelin oligodendrocyte glycoprotein-antibody (MOG-IgG) related illness with centrally positioned lengthy spinal wire lesion in a 14-month previous baby

Myelin oligodendrocyte glycoprotein-antibodies (MOG-IgG) are related to acquired inflammatory demyelinating syndromes, seen predominantly in youngsters and younger adults. The overlapping medical and radiological options of the heterogenous spectrum of demyelinating central nervous system (CNS) ailments makes the detection of MOG-IgG antibodies essential for prognosis and remedy choices.

Herein, we describe the incidence of MOG-IgG related illness presenting as acute disseminated encephalomyelitis (ADEM), with spinal MRI findings of centrally positioned lengthy wire lesion in a 14-month previous baby.

Auto-antibodies towards sort I IFNs in sufferers with life-threatening COVID-19

Interindividual medical variability in the middle of SARS-CoV-2 an infection is immense. We report that no less than 101 of 987 sufferers with life-threatening COVID-19 pneumonia had neutralizing IgG auto-Abs towards IFN-ω (13 sufferers), the 13 varieties of IFN-α (36), or each (52), on the onset of important illness; a couple of additionally had auto-Abs towards the opposite three sort I IFNs.

The auto-Abs neutralize the power of the corresponding sort I IFNs to dam SARS-CoV-2 an infection in vitro. These auto-Abs weren’t present in 663 people with asymptomatic or delicate SARS-CoV-2 an infection and had been current in solely four of 1,227 wholesome people. Sufferers with auto-Abs had been aged 25 to 87 years and 95 had been males. A B cell auto-immune phenocopy of inborn errors of sort I IFN immunity underlies life-threatening COVID-19 pneumonia in no less than 2.6% of ladies and 12.5% of males.

 

Blocking of the IL-33/ST2 Signaling Axis by a Single-Chain Antibody Variable Fragment (scFv) Particular to IL-33 with a Outlined Epitope

 

Interleukin 33 (IL-33) is an IL-1 household cytokine that performs a central function in immune system by regulating and initiating inflammatory responses. The binding of IL-33 to the suppressor of tumorigenicity 2 (ST2) receptor induces mitogen-activated protein kinases (MAPK) and nuclear issue κB (NF-κB) pathways, thereby resulting in inflammatory cytokines manufacturing in sort 2 helper T cells and sort 2 innate lymphoid cells.

 

To develop an antibody particular to IL-33 with an outlined epitope, we characterised a single-chain antibody variable fragments (scFvs) clone particular to IL-33, C2_2E12, which was chosen from a human artificial library of scFvs utilizing phage show. Affinity (Ok_d) of C2_2E12 was decided to be 38 nM utilizing enzyme-linked immunosorbent assay. C2_2E12 didn’t present cross-reactivity towards different interleukin cytokines, together with intently associated IL-1 household cytokines and unrelated proteins.

 

Mutational scanning evaluation revealed that the epitope of IL-33 consisted of residues 149-158 with key residues being L150 and Ok151 of IL-33. Structural modeling instructed that L150 and Ok151 residues are essential for the interplay of IL-33 with C2_2E12, implicating that C2_2E12 may block the binding of ST2 to IL-33. Pull-down and in-cell assays supported that C2_2E12 can inhibit the IL-33/ST2 signaling axis. These outcomes recommend that the scFv clone characterised right here can perform as a neutralizing antibody.

 

Interleukin-17 (IL-17) Human
GWB-21DD5F	GenWay Biotech	0.025 mg	Ask for price

Anti-Human IL-17 Antibody
101-M483	ReliaTech	100 µg	EUR 399
Description: The IL-17 family is comprised of at least six proinflammatory cytokines that share a conserved cysteine-knot structure but diverge at the N-terminus. IL-17 family members are glycoproteins secreted as dimers that induce local cytokine production and recruit granulocytes to sites of inflammation. IL-17 is induced by IL-15 and IL-23, mainly in activated CD4+ T cells distinct from Th1 or Th2 cells. IL-17F is the most homologous to IL-17, but is induced only by IL-23 in activated monocytes. IL-17B binds the IL-17B receptor, but not the IL-17 receptor; it is most homologous with IL-17D, which is expressed by resting CD4+ T cells and CD19+ B cells. IL-17E is mainly produced by Th2 cells and recruits eosinophils to lung tissue. IL-17C has a very restricted expression pattern but has been detected in adult prostate and fetal kidney libraries.

Human IL-17 protein
PRP100289-100ug	Abbkine	100 μg	EUR 1029
Description: Human IL-17 protein, expressed in E. coli

Human IL-17 protein
PRP100289-1mg	Abbkine	1 mg	EUR 7139
Description: Human IL-17 protein, expressed in E. coli

Human IL-17 protein
PRP100289-5ug	Abbkine	5 μg	EUR 149
Description: Human IL-17 protein, expressed in E. coli

Human IL-17 protein
PRP100290-100ug	Abbkine	100 μg	EUR 1029
Description: Human IL-17 protein, expressed in CHO Stable Cells

Human IL-17 protein
PRP100290-1mg	Abbkine	1 mg	EUR 6249
Description: Human IL-17 protein, expressed in CHO Stable Cells

Human IL-17 protein
PRP100290-5ug	Abbkine	5 μg	EUR 129
Description: Human IL-17 protein, expressed in CHO Stable Cells

Human IL-17 Protein
MBS9718710-0005mg	MyBiosource	0.005mg	EUR 165

Human IL-17 Protein
MBS9718710-002mg	MyBiosource	0.02mg	EUR 240

Human IL-17 Protein
MBS9718710-01mg	MyBiosource	0.1mg	EUR 720

Human IL-17 Protein
MBS9718710-5x01mg	MyBiosource	5x0.1mg	EUR 3195

Human IL-17 Protein
MBS9718711-0005mg	MyBiosource	0.005mg	EUR 135

Human IL-17 Protein
MBS9718711-002mg	MyBiosource	0.02mg	EUR 240

Human IL-17 Protein
MBS9718711-01mg	MyBiosource	0.1mg	EUR 720

Human IL-17 Protein
MBS9718711-1mg	MyBiosource	1mg	EUR 4090

Human IL-17 Protein
MBS9718711-5x1mg	MyBiosource	5x1mg	EUR 18370

Recombinant Human IL-17
HEILP-1702	Cyagen	5ug	Ask for price

Recombinant Human IL-17
SJB09-03	Amyotop	25µg/vial	EUR 307.2

anti- IL-17 antibody
FNab04224	FN Test	100µg	EUR 658.5
Description: Antibody raised against IL-17

anti- IL-17 antibody
FNab04225	FN Test	100µg	EUR 606.3
Description: Antibody raised against IL-17

Anti-IL-17 Antibody
ER1706-91	HUABIO	100ul	EUR 189
Description: Cytokines are small, soluble proteins with pleiotropic effects on a variety of cell types. Cytokines have a regulatory function over the immune system and mediate aspects of inflammatory response. They exert their biological effects through the binding of membrane-bound receptors which, in turn, initiate signal transduction cascades and elicit physiological changes in their target cell. Interleukin-17 (IL-17) and its cognate receptor, IL-17R, are an example of such a cytokine receptor pair. Originally identified as a rodent cDNA termed CTLA8, IL-17 is capable of inducing the secretion of IL-6 and IL-8 and augmenting the expression of ICAM-1 in human fibroblast cultures. The IL-17 protein exhibits a striking degree of homology with the HSV13 protein which mimics its function. The IL-17 receptor is a type I transmembrane protein 864 amino acids in length, that is highly expressed in spleen and kidney.

Anti-IL-17 Antibody
MBS822178-003mL	MyBiosource	0.03mL	EUR 185

Anti-IL-17 Antibody
MBS822178-01mL	MyBiosource	0.1mL	EUR 255

Anti-IL-17 Antibody
MBS822178-02mL	MyBiosource	0.2mL	EUR 335

Anti-IL-17 Antibody
MBS822178-5x02mL	MyBiosource	5x0.2mL	EUR 1420

Anti-IL-17 antibody
PAab04224	Nova Lifetech	100ug	EUR 275

Anti-IL-17 antibody
PAab04225	Nova Lifetech	100ug	EUR 245

Anti-Human IL-17 receptor Antibody
101-M484	ReliaTech	100 µg	EUR 399
Description: IL-17 binds to IL-17 receptors (IL-17 R), which share no homology with any known family of receptors. While the expression of IL-17 is restricted to activated T cells, IL-17 R mRNA exhibits a broad tissue distribution, and has been detected in virtually all cells and tissues tested. The amino acid sequence of human IL-17 R is 69% identical to mouse IL-17 R.

Human Interleukin 17 (IL-17) CLIA Kit
abx195860-96tests	Abbexa	96 tests	EUR 990

Human IL-17 -Interleukin 17- CLIA Kit
E-CL-H0104-24Tests	Elabscience Biotech	24 Tests	EUR 180
Description: Sandwich

Human IL-17 -Interleukin 17- CLIA Kit
E-CL-H0104-48Tests	Elabscience Biotech	48 Tests	EUR 546
Description: Sandwich

Human IL-17 -Interleukin 17- CLIA Kit
E-CL-H0104-96Tests	Elabscience Biotech	96 Tests	EUR 682
Description: Sandwich

Human IL-17 -Interleukin 17- CLIA Kit
E-CL-H0104-96Tests10	Elabscience Biotech	96 Tests *10	EUR 6820
Description: Sandwich

Human IL-17 -Interleukin 17- CLIA Kit
E-CL-H0104-96Tests5	Elabscience Biotech	96 Tests *5	EUR 3410
Description: Sandwich

Human IL-17 (Interleukin 17) CLIA Kit
MBS2532901-5x96Tests	MyBiosource	5x96Tests	EUR 2565

Human IL-17 (Interleukin 17) CLIA Kit
MBS2532901-96Tests	MyBiosource	96Tests	EUR 560

Human IL-17 (Interleukin 17) ELISA Kit
EKE60099-5x96T	Biomatik Corporation	5x96T	EUR 2667.6

Human IL-17 (Interleukin 17) ELISA Kit
EKE60099-96T	Biomatik Corporation	96T	EUR 561.6

Human Interleukin 17(IL-17) Elisa Kit
EK711084	AFG Bioscience LLC	96 Wells	EUR 0.14

Human IL-17(Interleukin 17) ELISA Kit
E39EH3267	EnoGene	96T	EUR 595

Human Interleukin 17,IL-17 ELISA Kit
CN-03335H1	ChemNorm	96T	EUR 520.8

Human Interleukin 17,IL-17 ELISA Kit
CN-03335H2	ChemNorm	48T	EUR 340.8

Human Interleukin 17,IL-17 ELISA Kit
YLA1538HU-48T	Shanghai YL Biotech	48T	Ask for price

Human Interleukin 17,IL-17 ELISA Kit
YLA1538HU-96T	Shanghai YL Biotech	96T	Ask for price

Human Interleukin 17(IL-17)ELISA Kit
GA-E0081HM-48Tests	GenAsia Biotech	48 Tests	Ask for price

Human Interleukin 17(IL-17)ELISA Kit
GA-E0081HM-96Tests	GenAsia Biotech	96 Tests	EUR 388

Human Interleukin 17(IL-17)ELISA Kit
GA-E0081HM-48T	GenAsia Biotech	48T	EUR 346.8

Human Interleukin 17(IL-17)ELISA Kit
GA-E0081HM-96T	GenAsia Biotech	96T	EUR 559.2

Human Interleukin 17(IL-17) ELISA Kit
NSL1920Hu	Sunlong	96 wells	EUR 468

Human Interleukin 17(IL-17)ELISA Kit
QY-E04323	Qayee Biotechnology	96T	EUR 433.2

Human Interleukin 17,IL-17 ELISA Kit
SL0978Hu	Sunlong	96 Tests	EUR 468

Human Interleukin 17,IL-17 ELISA KIT
E0142Hu-1096T	Jiaxing Korain Biotech Ltd (BT Labs)	10*96T	EUR 4122

Human Interleukin 17,IL-17 ELISA KIT
E0142Hu-48wells	Jiaxing Korain Biotech Ltd (BT Labs)	48 wells	EUR 300

Human Interleukin 17,IL-17 ELISA KIT
E0142Hu-596T	Jiaxing Korain Biotech Ltd (BT Labs)	5*96T	EUR 2061

Human Interleukin 17,IL-17 ELISA KIT
E0142Hu-96wells	Jiaxing Korain Biotech Ltd (BT Labs)	96 wells	EUR 458

Human Interleukin 17, IL-17 ELISA Kit
MBS162336-10x96StripWells	MyBiosource	10x96-Strip-Wells	EUR 3460

Human Interleukin 17, IL-17 ELISA Kit
MBS162336-48StripWells	MyBiosource	48-Strip-Wells	EUR 285

Human Interleukin 17, IL-17 ELISA Kit
MBS162336-5x96StripWells	MyBiosource	5x96-Strip-Wells	EUR 1750

Human Interleukin 17, IL-17 ELISA Kit
MBS162336-96StripWells	MyBiosource	96-Strip-Wells	EUR 425

Human IL-17 (Interleukin 17) ELISA Kit
MBS2501369-10x96Tests	MyBiosource	10x96Tests	EUR 3265

Human IL-17 (Interleukin 17) ELISA Kit
MBS2501369-24Tests	MyBiosource	24Tests	EUR 225

Human IL-17 (Interleukin 17) ELISA Kit
MBS2501369-48Tests	MyBiosource	48Tests	EUR 350

Human IL-17 (Interleukin 17) ELISA Kit
MBS2501369-5x96Tests	MyBiosource	5x96Tests	EUR 1655

Human IL-17 (Interleukin 17) ELISA Kit
MBS2501369-96Tests	MyBiosource	96Tests	EUR 395

Human Interleukin 17 (IL-17) ELISA Kit
MBS261470-10x96StripWells	MyBiosource	10x96-Strip-Wells	EUR 3040

Human Interleukin 17 (IL-17) ELISA Kit
MBS261470-48StripWells	MyBiosource	48-Strip-Wells	EUR 285

Human Interleukin 17 (IL-17) ELISA Kit
MBS261470-5x96StripWells	MyBiosource	5x96-Strip-Wells	EUR 1670

Human Interleukin 17 (IL-17) ELISA Kit
MBS261470-96StripWells	MyBiosource	96-Strip-Wells	EUR 405

Human Interleukin 17 (IL-17) ELISA Kit
MBS3800332-10x96StripWells	MyBiosource	10x96-Strip-Wells	EUR 6725

Human Interleukin 17 (IL-17) ELISA Kit
MBS3800332-48StripWells	MyBiosource	48-Strip-Wells	EUR 550

Human Interleukin 17 (IL-17) ELISA Kit
MBS3800332-5x96StripWells	MyBiosource	5x96-Strip-Wells	EUR 3420

Human Interleukin 17 (IL-17) ELISA Kit
MBS3800332-96StripWells	MyBiosource	96-Strip-Wells	EUR 765

Human Interleukin 17(IL-17) ELISA Kit
EIA05898h	Enlibio	each	EUR 430

Human Interleukin 17,IL-17 ELISA Kit
201-12-0143	Shanghai Sunred Biological Technology	96 tests	EUR 528
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human Interleukin-17 (IL-17) ELISA Kit
IHUIL17KT	Innovative research	each	EUR 702
Description: Human Interleukin-17 (IL-17) ELISA Kit

Human Interleukin-17 (IL-17) ELISA Kit
MBS8413481-1Kit	MyBiosource	1Kit	EUR 755

Human Interleukin-17 (IL-17) ELISA Kit
MBS8413481-5x1Kit	MyBiosource	5x1Kit	EUR 3455

Human IL-17 /IL-17A ELISA kit
E22-HC170.48	EnoGene	48T	EUR 295

Human IL-17 /IL-17A ELISA kit
E22-HC170.96	EnoGene	96T	EUR 395

Human IL-17/IL-17A ELISA Kit
MBS8579237-48Tests	MyBiosource	48Tests	EUR 390

Human IL-17/IL-17A ELISA Kit
MBS8579237-5x96Tests	MyBiosource	5x96Tests	EUR 2275

Human IL-17/IL-17A ELISA Kit
MBS8579237-96Tests	MyBiosource	96Tests	EUR 495

Recombinant Human Interleukin-17 (rHu IL-17)
MBS9419916-0025mL	MyBiosource	0.025mL	EUR 280

Recombinant Human Interleukin-17 (rHu IL-17)
MBS9419916-5x0025mL	MyBiosource	5x0.025mL	EUR 1120

IL-17 Interleukin-17 Human Recombinant Protein
PROTQ16552-1	BosterBio	Regular: 25ug	EUR 380.4
Description: Interleukin-17A Human Recombinant produced in E.Coli is a homodimeric, non-glycosylated polypeptide chain containing a total of 264 amino acids (2 chains of 132 aa) and having a molecular mass of 31kDa.  ;The IL-17 is purified by proprietary chromatographic techniques.

Recombinant Human IL-17 (IL-17A) Protein
PROTQ16552-4	BosterBio	25ug	EUR 380.4
Description: The originally described IL-17 protein, now known as IL-17A, is a homodimer of two 136 amino acid chains, secreted by activated T-cells that act on stromal cells to induce production of proinflammatory and hematopoietic bioactive molecules.  Today, IL-17 represents a family of structurally-related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles.  The six known members of this family, IL-17A through IL-17F, are secreted as homodimers.  IL-17A exhibits cross-species bioactivity between human and murine cells.  Recombinant human IL-17A is a 31.3 kDa disulfide-linked homodimer of two 137 amino acid polypeptide chains.

Recombinant Human IL-17/IL-17A Protein
RP00395	Abclonal	10μg	EUR 134.62

Recombinant Human IL-17/IL-17A Protein
RP00821	Abclonal	10μg	EUR 85.02

human IL-17, His tag
E410A10-100	EnoGene	100μg	EUR 700
Description: Inflammation Storm Cytokine

human IL-17, His tag
MBS8574809-01mg	MyBiosource	0.1mg	EUR 505

human IL-17, His tag
MBS8574809-5x01mg	MyBiosource	5x0.1mg	EUR 2015

Anti-Human IL-17 (IL-17A) Goat Polyclonal Antibody
TA328238	Origene Technologies GmbH	100 µg	Ask for price

Anti-Human IL-17 (IL-17A) Rabbit Polyclonal Antibody
TA328239	Origene Technologies GmbH	100 µg	Ask for price

Human IL-17 ELISA Kit
E16HE0054	EnoGene	96T	EUR 733.33

Human IL-17 ELISA KIT
E16HE0054-048	EnoGene	48 wells	EUR 295

Human IL-17 ELISA KIT
E16HE0054-096	EnoGene	96 wells	EUR 395

Human IL-17 ELISA KIT
E42EH-11	EnoGene	96T/48T	Ask for price

IL-17 (Human) ELISA Kit
E4628-100	Biovision	each	EUR 874.8

Human IL-17 ELISA KIT
EF006939	Nova Lifetech	96tests	EUR 566

Human IL-17 ELISA Kit
GWB-ZZD054	GenWay Biotech	1x96 well plate	Ask for price

Human IL-17 ELISA kit
LF-EK50201	Abfrontier	1×96T	EUR 777.6

Human IL-17 ELISA Kit
RK00397	Abclonal	96 Tests	EUR 280

Human IL-17 ELISA KIT
MBS9424822-5x96Tests	MyBiosource	5x96Tests	EUR 2225

Human IL-17 ELISA KIT
MBS9424822-96Tests	MyBiosource	96Tests	EUR 485

Human IL-17 ELISA Kit
MBS8244675-5x96Tests	MyBiosource	5x96Tests	EUR 2755

Human IL-17 ELISA Kit
MBS8244675-96Tests	MyBiosource	96Tests	EUR 620

Human IL-17 ELISA Kit
MBS824670-5x96Tests	MyBiosource	5x96Tests	EUR 2755

Human IL-17 ELISA Kit
MBS824670-96Tests	MyBiosource	96Tests	EUR 620

Human IL-17 ELISA Kit
MBS9135954-5x96Tests	MyBiosource	5x96Tests	EUR 2615

Human IL-17 ELISA Kit
MBS9135954-96Tests	MyBiosource	96Tests	EUR 570

Human IL-17 ELISA KIT
MBS8506110-48Wells	MyBiosource	48Wells	EUR 390

Human IL-17 ELISA KIT
MBS8506110-5x96Wells	MyBiosource	5x96Wells	EUR 2275

Human IL-17 ELISA KIT
MBS8506110-96Wells	MyBiosource	96Wells	EUR 495

Human IL-17 ELISA Kit
MBS824986-5x96Tests	MyBiosource	5x96Tests	EUR 2755

Human IL-17 ELISA Kit
MBS824986-96Tests	MyBiosource	96Tests	EUR 620

IL-17 Human ELISA Kit
MBS355268-5x96Tests	MyBiosource	5x96Tests	EUR 2190

IL-17 Human ELISA Kit
MBS355268-96Tests	MyBiosource	96Tests	EUR 485

Human IL-17 ELISA Kit
MBS9719278-48Tests	MyBiosource	48Tests	EUR 300

Human IL-17 ELISA Kit
MBS9719278-5x48Tests	MyBiosource	5x48Tests	EUR 1365

Human IL-17 ELISA Kit
MBS9719278-5x96Tests	MyBiosource	5x96Tests	EUR 1750

Human IL-17 ELISA Kit
MBS9719278-96Tests	MyBiosource	96Tests	EUR 385

Human IL-17 GENLISA ELISA
KBH0142	Krishgen	1 x 96 wells	EUR 286

Recombinant Human IL-17 protein
CD01557-5ug	Jiaxing Korain Biotech Ltd (BT Labs)	5ug	EUR 176
Description: Human Interleukin-17A (IL-17A) is encoded by the IL17A gene located on the chromosome 6 and belongs to the IL-17 family that contains IL-17A, IL-17B, IL-17C, IL-17D, IL-17E and IL-17F. They have a similar protein structure, with four highly conserved cysteine residues critical to their 3-dimensional shape, but no sequence similarity to any other known cytokines. Interleukin 17 is a T cell-expressed pleiotropic cytokine that exhibits a high degree of homology to a protein encoded by the ORF13 gene of herpesvirus Saimiri. Mature IL-17 containing one potential N-linked glycosylation site. Both recombinant and natural IL-17 have been shown to exist as disulfide linked homodimers. At the amino acid level, IL-17 exhibits 63 % amino acid identity with mouse IL-17. High levels of human IL-17 were induced from primary peripheral blood CD4+ T cells upon stimulation and they can induce stromal cells to produce proinflammatory and hematopoietic cytokines.

Anti-Mouse IL-17 Antibody
103-M411	ReliaTech	100 µg	EUR 399
Description: The IL-17 family is comprised of at least six proinflammatory cytokines that share a conserved cysteine-knot structure but diverge at the N-terminus. IL-17 family members are glycoproteins secreted as dimers that induce local cytokine production and recruit granulocytes to sites of inflammation. IL-17 is induced by IL-15 and IL-23, mainly in activated CD4+ T cells distinct from Th1 or Th2 cells. IL-17F is the most homologous to IL-17, but is induced only by IL-23 in activated monocytes. IL-17B binds the IL-17B receptor, but not the IL-17 receptor; it is most homologous with IL-17D, which is expressed by resting CD4+ T cells and CD19+ B cells. IL-17E is mainly produced by Th2 cells and recruits eosinophils to lung tissue. IL-17C has a very restricted expression pattern but has been detected in adult prostate and fetal kidney libraries.

Anti-IL-17 alpha antibody
STJ93683	St John's Laboratory	200 µl	EUR 236.4
Description: Rabbit polyclonal to IL-17Ralpha.

Rabbit anti-IL-17 Antibody
DL90598A-100ul	DL Develop	100 ul	EUR 299
Description: CTLA8; IL17; Interleukin-17A; IL-17; IL-17A; Cytotoxic T-lymphocyte-associated antigen 8; CTLA-8

Rabbit anti-IL-17 Antibody
DL90598A-50ul	DL Develop	50 ul	EUR 209.3
Description: CTLA8; IL17; Interleukin-17A; IL-17; IL-17A; Cytotoxic T-lymphocyte-associated antigen 8; CTLA-8

Rabbit anti-IL-17 Antibody
YLD4293-100ul	Shanghai YL Biotech	100 ul	EUR 320
Description: Rabbit polyclonal antibody to IL-17

Rabbit anti-IL-17 Antibody
YLD4293-50ul	Shanghai YL Biotech	50 ul	EUR 200
Description: Rabbit polyclonal antibody to IL-17

Anti-Human IL-17 (CTLA-8) Antibody
101-M783	ReliaTech	100 µg	EUR 399
Description: The IL-17 family is comprised of at least six proinflammatory cytokines that share a conserved cysteine-knot structure but diverge at the N-terminus. IL-17 family members are glycoproteins secreted as dimers that induce local cytokine production and recruit granulocytes to sites of inflammation. IL-17 is induced by IL-15 and IL-23, mainly in activated CD4+ T cells distinct from Th1 or Th2 cells. IL-17F is the most homologous to IL-17, but is induced only by IL-23 in activated monocytes. IL-17B binds the IL-17B receptor, but not the IL-17 receptor; it is most homologous with IL-17D, which is expressed by resting CD4+ T cells and CD19+ B cells. IL-17E is mainly produced by Th2 cells and recruits eosinophils to lung tissue. IL-17C has a very restricted expression pattern but has been detected in adult prostate and fetal kidney libraries.

CLIA kit for Human IL-17 (Interleukin 17)
E-CL-H0104	Elabscience Biotech	1 plate of 96 wells	EUR 700.8
Description: A sandwich CLIA kit for quantitative measurement of Human IL-17 (Interleukin 17) in samples from Serum, Plasma, Cell supernatant

ELISA kit for Human IL-17 (Interleukin 17)
E-EL-H0105	Elabscience Biotech	1 plate of 96 wells	EUR 452.4
Description: A sandwich ELISA kit for quantitative measurement of Human IL-17 (Interleukin 17) in samples from Serum, Plasma, Cell supernatant

Human Interleukin 17 (IL-17) Detection Assay Kit
6808	Chondrex	1 kit	EUR 357
Description: Culture Media, Serum, Plasma

IL-17 Interleukin-17 Human Recombinant Protein, HEK
PROTQ16552	BosterBio	Regular: 10ug	EUR 380.4
Description: IL-17 Human Recombinant produced in HEK cells is a glycosylated homodimer, having a molecular weight range of 30-35kDa due to glycosylation.;The IL-17 is purified by proprietary chromatographic techniques.

Biotinylated Anti-Human IL-17 (IL-17A) Goat Polyclonal Antibody
TA328237	Origene Technologies GmbH	50 µg	Ask for price

Biotinylated Anti-Human IL-17 (IL-17A) Rabbit Polyclonal Antibody
TA328236	Origene Technologies GmbH	50 µg	Ask for price

ELISA kit for Human IL-17
KET6022-48T	Abbkine	48T	EUR 242.4
Description: Quantitative sandwich ELISA for measuring Human IL-17 in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human IL-17
KET6022-5platesof96wells	Abbkine	5 plates of 96 wells	EUR 1292.4
Description: Quantitative sandwich ELISA for measuring Human IL-17 in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human IL-17
KET6022-96T	Abbkine	96T	EUR 346.8
Description: Quantitative sandwich ELISA for measuring Human IL-17 in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Anti‐Human IL‐17A
E2790213	EnoGene	100ul	EUR 225
Description: Available in various conjugation types.

Human IL-17 ELISA kit (4X96T)
LF-EK50202	Abfrontier	4×96T	EUR 2641.2

Human IL-17 protein, His Tag
PRP100287-100ug	Abbkine	100 μg	EUR 779
Description: Human IL-17 protein, His Tag, expressed in Baculovirus-Insect Cells

Human IL-17 protein, His Tag
PRP100287-1mg	Abbkine	1 mg	EUR 4959
Description: Human IL-17 protein, His Tag, expressed in Baculovirus-Insect Cells

Human IL-17 protein, His Tag
PRP100288-100ug	Abbkine	100 μg	EUR 779
Description: Human IL-17 protein, His Tag, expressed in Yeast

Human IL-17 protein, His Tag
PRP100288-1mg	Abbkine	1 mg	EUR 4959
Description: Human IL-17 protein, His Tag, expressed in Yeast

Human IL-17 Protein, His Tag
MBS9718708-0005mg	MyBiosource	0.005mg	EUR 165

Human IL-17 Protein, His Tag
MBS9718708-002mg	MyBiosource	0.02mg	EUR 240

Human IL-17 Protein, His Tag
MBS9718708-005mg	MyBiosource	0.05mg	EUR 430

Human IL-17 Protein, His Tag
MBS9718708-01mg	MyBiosource	0.1mg	EUR 560

Human IL-17 Protein, His Tag
MBS9718708-5x01mg	MyBiosource	5x0.1mg	EUR 2475

Human IL-17 Protein, His Tag
MBS9718709-005mg	MyBiosource	0.05mg	EUR 355

Human IL-17 Protein, His Tag
MBS9718709-01mg	MyBiosource	0.1mg	EUR 560

Human IL-17 Protein, His Tag
MBS9718709-5x01mg	MyBiosource	5x0.1mg	EUR 2475

Human IL-17 protein, His Tag
PRP100287-each	Abbkine	each	Ask for price

Human IL-17 protein, His Tag
PRP100288-each	Abbkine	each	Ask for price

CymaxTM Human IL-17 ELISA Kit
LF-EK0295	Abfrontier	1×96T	EUR 477.6

Human IL-17 PicoKine ELISA Kit
MBS175886-5x96StripWells	MyBiosource	5x96-Strip-Wells	EUR 2755

Human IL-17 PicoKine ELISA Kit
MBS175886-96StripWells	MyBiosource	96-Strip-Wells	EUR 600

IL-17 (Human) OmniKine ELISA Kit
MBS9502089-1x96Wells	MyBiosource	1x96Wells	EUR 500

IL-17 (Human) OmniKine ELISA Kit
MBS9502089-5x96Wells	MyBiosource	5x96Wells	EUR 2300

IL-17 (Human) Sandwich ELISA Kit
OK-0368	Assay Biotech	1Kit	EUR 280
Description: IL-17 (Human) Colorimetric Sandwich ELISA Kit

Human IL-17 (Interleukin-17) Pre-Coated ELISA Kit
MBS669199-5x96Tests	MyBiosource	5x96Tests	EUR 3545

Human IL-17 (Interleukin-17) Pre-Coated ELISA Kit
MBS669199-96Tests	MyBiosource	96Tests	EUR 770

Human High Sensitive Interleukin 17 (IL-17) ELISA Kit
MBS284238-10x96StripWells	MyBiosource	10x96-Strip-Wells	EUR 6840