Past Allotypes: The Affect of Allelic Variety in Antibody Fixed Domains
Polymorphic variety in antibody fixed domains has lengthy been outlined by allotypic motifs that cross react with the sera of different people. Enhancements in sequencing applied sciences have led to the invention of a lot of new allelic sequences that underlie this variety.
Most of the level mutations lie outdoors conventional allotypic motifs suggesting they don’t elicit immunogenic responses. As antibodies play an essential position in immune protection and biotechnology, understanding how this newly resolved variety influences the perform of antibodies is essential.
This overview investigates the present identified variety of antibody alleles at a protein stage for every antibody isotype in addition to the kappa and lambda mild chains.
We deal with proof rising for the way these mutations perturb antibody interactions with antigens and Fc receptors which are crucial for perform, as effectively because the affect this may need on the usage of antibodies as therapeutics and reagents.

toxhistory
GRO, KC, CXCL1, rRtGRO, rat |
RC352-12 |
Bio Basic |
5ug |
EUR 125.26 |
|
GRO/KC (CXCL1), Rat Recombinant |
P1288-25 |
Biovision |
each |
EUR 444 |
GRO/KC (CXCL1), Rat Recombinant |
P1288-5 |
Biovision |
each |
EUR 210 |
Recombinant Murine KC (CXCL1) Protein |
PROTP12850-2 |
BosterBio |
20ug |
EUR 380.4 |
Description: All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. Recombinant murine KC is a 7.8 kDa protein consisting of 72 amino acids including the 'ELR' motif common to the CXC chemokine family that bind to CXCR1 or CXCR2. |
Recombinant Rat GRO/KC (CXCL1) Protein |
PROTP14095-1 |
BosterBio |
25ug |
EUR 380.4 |
Description: All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. Recombinant rat GRO/KC is a 7.8 kDa protein consisting of 72 amino acids including the 'ELR' motif common to the CXC chemokine family that bind to CXCR1 or CXCR2. |
Rat CXCL1/CINC-1/KC ELISA Kit |
RK00196 |
Abclonal |
96 Tests |
EUR 625.2 |
Mouse CXCL1 ELISA Kit |
55R-1741 |
Fitzgerald |
1 kit |
EUR 748.8 |
Description: ELISA kit for detection of CXCL1 in the research laboratory |
Mouse CXCL1 shRNA Plasmid |
20-abx970673 |
Abbexa |
|
|
|
ELISA kit for Mouse CXCL1 |
EK5299 |
SAB |
96 tests |
EUR 663.6 |
Description: Enzyme-linked immunosorbent assay kit for quantification of Mouse CXCL1 in samples from serum, plasma, tissue homogenates and other biological fluids. |
Mouse CXCL1/GROα ELISA kit |
LF-EK50473 |
Abfrontier |
1×96T |
EUR 777.6 |
Mouse CXCL1 PicoKine ELISA Kit |
EK0723 |
BosterBio |
96 wells |
EUR 547.2 |
Description: For quantitative detection of mouse CXCL1 in cell culture supernates and serum. |
Mouse CXCL1 Detection Assay Kit |
6725 |
Chondrex |
1 kit |
EUR 580.26 |
Description: Mouse CXCL1 Detection Assay Kit |
CXCL1 protein (Mouse) (His tag) |
80R-3368 |
Fitzgerald |
50 ug |
EUR 308.4 |
Description: Purified recombinant CXCL1 protein (Mouse) (His tag) |
CXCL1 protein (Mouse) (His tag) |
80R-3439 |
Fitzgerald |
50 ug |
EUR 308.4 |
Description: Purified recombinant CXCL1 protein (Mouse) (His tag) |
Cxcl1 ORF Vector (Mouse) (pORF) |
ORF042286 |
ABM |
1.0 ug DNA |
EUR 114 |
Mouse CXCL1 AssayLite Antibody (FITC Conjugate) |
70027-05141 |
AssayPro |
150 ug |
EUR 513.6 |
CXCL1 ELISA Kit (Mouse) (OKBB00312) |
OKBB00312 |
Aviva Systems Biology |
96 Tests |
EUR 652.8 |
Description: Description of target: Chemokine (C-X-C motif) ligand 1 (CXCL1) is a small cytokine belonging to the CXC chemokine family that was previously called GRO1 oncogene, GROα, KC, Neutrophil-activating protein 3 (NAP-3) and melanoma growth stimulating activity, alpha (MSGA-α). In humans, this protein is encoded by the CXCL1 gene. The gene for CXCL1 is located on human chromosome 4 amongst genes for other CXC chemokines. The mature form of CXCL1 is maximally 73 amino acids long. CXCL1 is secreted by human melanoma cells, has mitogenic properties and is implicated in melanoma pathogenesis. CXCL1 is expressed by macrophages, neutrophils and epithelial cells, and has neutrophil chemoattractant activity. This chemokine elicits its effects by signaling through the chemokine receptor CXCR2.CXCL1 decreased the severity of multiple sclerosis and may offer a neuro-protective function. The standard product used in this kit is recombinant mouse CXCL1, consisting of 77 amino acids with the molecular mass of 8KDa.;Species reactivity: Mouse;Application: ELISA;Assay info: ;Sensitivity: < 1 pg/ml |
CXCL1 ELISA Kit (Mouse) (OKAN04583) |
OKAN04583 |
Aviva Systems Biology |
96 Wells |
EUR 950.4 |
Description: Description of target: This gene encodes a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This secretory protein is proposed to bind the G-protein coupled receptor chemokine (C-X-C motif) receptor 2 to recruit neutrophils. In mouse, deficiency of this gene is associated with colitis and with defects in immune cell recruitment to the lung.;Species reactivity: Mouse;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 6.0 pg/mL |
CXCL1 ELISA Kit (Mouse) (OKCD05712) |
OKCD05712 |
Aviva Systems Biology |
96 Wells |
EUR 730.8 |
Description: Description of target: This gene encodes a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This secretory protein is proposed to bind the G-protein coupled receptor chemokine (C-X-C motif) receptor 2 to recruit neutrophils. In mouse, deficiency of this gene is associated with colitis and with defects in immune cell recruitment to the lung.;Species reactivity: Mouse;Application: ELISA;Assay info: ;Sensitivity: < 6.0pg/mL |
Mouse CXCL1/GROα ELISA kit (4X96T) |
LF-EK50474 |
Abfrontier |
4×96T |
EUR 2641.2 |
Anti-GRO alpha/Cxcl1 Antibody |
A00533 |
BosterBio |
100ug/vial |
EUR 352.8 |
Anti-GRO alpha/CXCL1 Antibody |
PA1760 |
BosterBio |
100ug/vial |
EUR 352.8 |
CXCL1 Antibody |
43679-100ul |
SAB |
100ul |
EUR 302.4 |
CXCL1 antibody |
70R-10502 |
Fitzgerald |
50 ug |
EUR 560.4 |
Description: Affinity purified rabbit polyclonal CXCL1 antibody |
CXCL1 antibody |
70R-14297 |
Fitzgerald |
100 ug |
EUR 392.4 |
Description: Affinity purified Rabbit polyclonal CXCL1 antibody |
CXCL1 antibody |
70R-16681 |
Fitzgerald |
50 ul |
EUR 522 |
Description: Rabbit polyclonal CXCL1 antibody |
CXCL1 antibody |
70R-15473 |
Fitzgerald |
100 ug |
EUR 392.4 |
Description: Rabbit polyclonal CXCL1 antibody |
CXCL1 Antibody |
33054-100ul |
SAB |
100ul |
EUR 302.4 |
CXCL1 Antibody |
1-CSB-PA006239GA01HU |
Cusabio |
|
|
|
Description: A polyclonal antibody against CXCL1. Recognizes CXCL1 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC |
CXCL1 Antibody |
1-CSB-PA06097A0Rb |
Cusabio |
|
|
|
Description: A polyclonal antibody against CXCL1. Recognizes CXCL1 from Human. This antibody is Unconjugated. Tested in the following application: ELISA |
CXCL1 Antibody |
1-CSB-PA009036 |
Cusabio |
|
|
|
Description: A polyclonal antibody against CXCL1. Recognizes CXCL1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: IHC, ELISA;IHC:1/100-1/300.ELISA:1/10000 |
Cxcl1 Antibody |
1-CSB-PA09217A0Rb |
Cusabio |
|
|
|
Description: A polyclonal antibody against Cxcl1. Recognizes Cxcl1 from Mouse. This antibody is Unconjugated. Tested in the following application: ELISA |
GRO-alpha/CXCL1 (CHO-expressed), Mouse |
HY-P7186 |
MedChemExpress |
50ug |
EUR 404.4 |
Cxcl1 sgRNA CRISPR Lentivector set (Mouse) |
K4368201 |
ABM |
3 x 1.0 ug |
EUR 406.8 |
Mouse Growth-regulated alpha protein (Cxcl1) |
1-CSB-RP092174m |
Cusabio |
-
EUR 606.00
-
EUR 318.00
-
EUR 2192.40
-
EUR 919.20
-
EUR 1461.60
-
EUR 402.00
|
- 100ug
- 10ug
- 1MG
- 200ug
- 500ug
- 50ug
|
|
Description: Recombinant Mouse Growth-regulated alpha protein(Cxcl1),partial expressed in E.coli |
CXCL1 Protein Vector (Mouse) (pPM-C-HA) |
PV169144 |
ABM |
500 ng |
EUR 723.6 |
Cxcl1 ELISA Kit (Mouse) : 96 Wells (OKEH02714) |
OKEH02714 |
Aviva Systems Biology |
96 Wells |
EUR 652.8 |
Description: Description of target: This gene encodes a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This secretory protein is proposed to bind the G-protein coupled receptor chemokine (C-X-C motif) receptor 2 to recruit neutrophils. In mouse, deficiency of this gene is associated with colitis and with defects in immune cell recruitment to the lung. ;Species reactivity: Mouse;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 15.76 pg/mL |
CXCL1 Protein Vector (Mouse) (pPB-C-His) |
PV169142 |
ABM |
500 ng |
EUR 723.6 |
CXCL1 Protein Vector (Mouse) (pPB-N-His) |
PV169143 |
ABM |
500 ng |
EUR 723.6 |
CXCL1 Protein Vector (Mouse) (pPM-C-His) |
PV169145 |
ABM |
500 ng |
EUR 723.6 |
CXCL1 antibody (HRP) |
60R-2236 |
Fitzgerald |
100 ug |
EUR 392.4 |
Description: Rabbit polyclonal CXCL1 antibody (HRP) |
CXCL1 antibody (FITC) |
60R-2237 |
Fitzgerald |
100 ug |
EUR 392.4 |
Description: Rabbit polyclonal CXCL1 antibody (FITC) |
CXCL1/GRO |
E21-597 |
EnoGene |
10ug |
EUR 411.6 |
Cxcl1 sgRNA CRISPR Lentivector (Mouse) (Target 1) |
K4368202 |
ABM |
1.0 ug DNA |
EUR 184.8 |
Cxcl1 sgRNA CRISPR Lentivector (Mouse) (Target 2) |
K4368203 |
ABM |
1.0 ug DNA |
EUR 184.8 |
Cxcl1 sgRNA CRISPR Lentivector (Mouse) (Target 3) |
K4368204 |
ABM |
1.0 ug DNA |
EUR 184.8 |
CXCL1 antibody (biotin) |
60R-2238 |
Fitzgerald |
100 ug |
EUR 392.4 |
Description: Rabbit polyclonal CXCL1 antibody (biotin) |
CXCL1 siRNA |
20-abx913248 |
Abbexa |
|
|
|
CXCL1 siRNA |
20-abx913249 |
Abbexa |
|
|
|
CXCL1 siRNA |
20-abx901350 |
Abbexa |
|
|
|
CXCL1 protein |
30R-3156 |
Fitzgerald |
50 ug |
EUR 308.4 |
Description: Purified recombinant CXCL1 protein |
CXCL1 Peptide |
42-129P |
ProSci |
0.1 mg |
EUR 405.6 |
Description: (CT) CXCL1 Peptide |
CXCL1 Conjugated Antibody |
C33054 |
SAB |
100ul |
EUR 476.4 |
Cxcl1 Polyclonal Antibody |
A51950 |
EpiGentek |
-
EUR 684.66
-
EUR 117.70
-
EUR 302.50
-
EUR 423.50
|
- 100 µg
- 20 ul
- 50 ul
- 100 ul
|
CXCL1 Polyclonal Antibody |
A51978 |
EpiGentek |
-
EUR 684.66
-
EUR 117.70
-
EUR 302.50
-
EUR 423.50
|
- 100 µg
- 20 ul
- 50 ul
- 100 ul
|
CXCL1 Chemi-Luminescent ELISA Kit (Mouse) (OKCD03823) |
OKCD03823 |
Aviva Systems Biology |
96 Wells |
EUR 1232.4 |
Description: Description of target: Has chemotactic activity for neutrophils. Contributes to neutrophil activation during inflammation . Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. KC(5-72) shows a highly enhanced hematopoietic activity.;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 15.6 pg/mL |
Mouse Cxcl1/ Growth-regulated alpha protein ELISA Kit |
E0354Mo |
Sunlong |
1 Kit |
EUR 655.2 |
Mouse Growth regulated alpha protein, Cxcl1 ELISA KIT |
ELI-04012m |
Lifescience Market |
96 Tests |
EUR 1038 |
GRO alpha (CXCL1) Antibody |
abx018005-100ug |
Abbexa |
100 ug |
EUR 410.4 |
|
Gro alpha Antibody / CXCL1 |
RQ4031 |
NSJ Bioreagents |
100 ug |
EUR 356.15 |
Description: CXCL1 (Chemokine, CXC motif, Ligand 1), also called GRO1, SCYB1, GROA or MGSA, is a small cytokine belonging to the CXC chemokine family that was previously called GRO1 oncogene, GRO?, KC, Neutrophil-activating protein 3 (NAP-3) and melanoma growth stimulating activity, alpha (MSGA-?). In humans, this protein is encoded by the CXCL1 gene. The CXCL1 gene is mapped on 4q13.3. CXCL1 is secreted by human melanoma cells, has mitogenic properties and is implicated in melanoma pathogenesis. It is expressed by macrophages, neutrophils and epithelial cells, and has neutrophil chemoattractant activity. CXCL1 plays a role in spinal cord development by inhibiting the migration of oligodendrocyte precursors and is involved in the processes of angiogenesis, inflammation, wound healing, and tumorigenesis. Signaling through Cxcr2, Cxcl1 inhibited oligodendrocyte precursor migration. The migrational arrest was rapid, reversible, and concentration dependent, and it reflected enhanced cell/substrate interactions. White matter expression of Cxcl1 was temporospatially regulated. Others contribute to aggressive growth selectivity in the lung. Among the lung metastasis signature genes identified, several, including CXCL1, were functionally validated. |
Mouse Growth-Regulated Alpha Protein (CXCL1) ELISA Kit |
abx253956-96tests |
Abbexa |
96 tests |
EUR 801.6 |
|
Mouse Growth-Regulated Alpha Protein (CXCL1) ELISA Kit |
20-abx154438 |
Abbexa |
-
EUR 6373.20
-
EUR 3404.40
-
EUR 801.60
|
- 10 × 96 tests
- 5 × 96 tests
- 96 tests
|
|
Mouse Growth-Regulated Alpha Protein (CXCL1) ELISA Kit |
abx050043-96tests |
Abbexa |
96 tests |
EUR 924 |
|
Mouse Growth-Regulated Alpha Protein (CXCL1) ELISA Kit |
abx574645-96tests |
Abbexa |
96 tests |
EUR 801.6 |
|
Mouse CXCL1/GROα(Growth Regulated Oncogene Alpha) ELISA Kit |
EM0003 |
FN Test |
96T |
EUR 571.5 |
|
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 9.375pg/ml |
CXCL1 Antibody, HRP conjugated |
1-CSB-PA06097B0Rb |
Cusabio |
|
|
|
Description: A polyclonal antibody against CXCL1. Recognizes CXCL1 from Human. This antibody is HRP conjugated. Tested in the following application: ELISA |
Cxcl1 Antibody, HRP conjugated |
1-CSB-PA09217B0Rb |
Cusabio |
|
|
|
Description: A polyclonal antibody against Cxcl1. Recognizes Cxcl1 from Mouse. This antibody is HRP conjugated. Tested in the following application: ELISA |
CXCL1 Antibody, FITC conjugated |
1-CSB-PA06097C0Rb |
Cusabio |
|
|
|
Description: A polyclonal antibody against CXCL1. Recognizes CXCL1 from Human. This antibody is FITC conjugated. Tested in the following application: ELISA |
Cxcl1 Antibody, FITC conjugated |
1-CSB-PA09217C0Rb |
Cusabio |
|
|
|
Description: A polyclonal antibody against Cxcl1. Recognizes Cxcl1 from Mouse. This antibody is FITC conjugated. Tested in the following application: ELISA |
CXCL1 Antibody, Biotin conjugated |
1-CSB-PA06097D0Rb |
Cusabio |
|
|
|
Description: A polyclonal antibody against CXCL1. Recognizes CXCL1 from Human. This antibody is Biotin conjugated. Tested in the following application: ELISA |
Cxcl1 Antibody, Biotin conjugated |
1-CSB-PA09217D0Rb |
Cusabio |
|
|
|
Description: A polyclonal antibody against Cxcl1. Recognizes Cxcl1 from Mouse. This antibody is Biotin conjugated. Tested in the following application: ELISA |
Recombinant Mouse CXCL1/ GRO-alpha Protein, Untagged, E.coli-1mg |
QP1455-1mg |
EnQuireBio |
1mg |
EUR 3427.2 |
Recombinant Mouse CXCL1/ GRO-alpha Protein, Untagged, E.coli-5ug |
QP1455-5ug |
EnQuireBio |
5ug |
EUR 163.2 |
Recombinant Mouse CXCL1/ GRO-alpha Protein, Untagged, E.coli-20ug |
QP1455-20ug |
EnQuireBio |
20ug |
EUR 284.4 |
Mouse Growth Regulated Oncogene Alpha / GROa (CXCL1) CLIA Kit |
abx196070-96tests |
Abbexa |
96 tests |
EUR 990 |
|
CXCL1 cloning plasmid |
CSB-CL006239HU-10ug |
Cusabio |
10ug |
EUR 279.6 |
|
Description: A cloning plasmid for the CXCL1 gene. |
Recombinant Mouse CXCL1/ MGSA/ NAP-3 Protein, His, E.coli-1mg |
QP8650-ec-1mg |
EnQuireBio |
1mg |
EUR 2763.6 |
Recombinant Mouse CXCL1/ GRO-alpha Protein, Untagged, E.coli-100ug |
QP1455-100ug |
EnQuireBio |
100ug |
EUR 588 |
Recombinant Mouse CXCL1/ GRO-alpha Protein, Untagged, E.coli-500ug |
QP1455-500ug |
EnQuireBio |
500ug |
EUR 2133.6 |
CXCL1 Blocking Peptide |
20-abx061039 |
Abbexa |
|
|
|
CXCL1 Blocking Peptide |
33R-7741 |
Fitzgerald |
100 ug |
EUR 216 |
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of CXCL1 antibody, catalog no. 70R-10502 |
Recombinant Mouse CXCL1/ MGSA/ NAP-3 Protein, His, E.coli-10ug |
QP8650-ec-10ug |
EnQuireBio |
10ug |
EUR 326.4 |
Recombinant Mouse CXCL1/ MGSA/ NAP-3 Protein, His, E.coli-50ug |
QP8650-ec-50ug |
EnQuireBio |
50ug |
EUR 434.4 |
Recombinant Human CXCL1 |
P0109 |
FN Test |
100ug |
EUR 626.83 |
|
Description: Recombinant Human protein for CXCL1 |
Recombinant Human CXCL1 |
P0207 |
FN Test |
100ug |
EUR 626.83 |
|
Description: Recombinant Human protein for CXCL1 |
Recombinant Mouse CXCL1/ MGSA/ NAP-3 Protein, His, E.coli-100ug |
QP8650-ec-100ug |
EnQuireBio |
100ug |
EUR 685.2 |
Recombinant Mouse CXCL1/ MGSA/ NAP-3 Protein, His, E.coli-200ug |
QP8650-ec-200ug |
EnQuireBio |
200ug |
EUR 1077.6 |
Recombinant Mouse CXCL1/ MGSA/ NAP-3 Protein, His, E.coli-500ug |
QP8650-ec-500ug |
EnQuireBio |
500ug |
EUR 1816.8 |
CXCL1 Recombinant Protein |
91-532 |
ProSci |
0.05 mg |
EUR 714.3 |
Description: Chemokine (C-X-C motif) Ligand 1 Protein (CXCL1) is a growth factor for melanoma cells and a chemotaxin for neutrophils and a member of the CXC chemokine family that is a potent neutrophil attractant and activator and is also active toward basophils. CXCL1 is expressed by macrophages, neutrophils and epithelial cells; it has neutrophil chemoattractant activity. CXCL1 plays a critical nonredundant role in the development of experimental Lyme arthritis and carditis via CXCR2-mediated recruitment of neutrophils into the site of infection and may also have important pro-nociceptive effects via its direct actions on sensory neurons, and may induce long-term changes that involve protein synthesis. |
CXCL1 Recombinant Protein |
91-628 |
ProSci |
0.05 mg |
EUR 651.3 |
Description: Cxcl1, also called Gro, Gro1, Mgsa or Scyb1, is short for growth-regulated alpha protein. The protein belongs to the intercrine alpha (chemokine CxC) family. The N-terminal processed form KC(5-72) of the protein is produced by proteolytic cleavage after secretion from bone marrow stromal cells, and shows a highly enhanced hematopoietic activity. Cxcl1 has chemotactic activity for neutrophils, and contributes to neutrophil activation during inflammation. Hematoregulatory chemokine, in vitro, suppresses hematopoietic progenitor cell proliferation. |
Recombinant Mouse CXCL1/ MGSA/ NAP-3 Protein, Untagged, E.coli-5ug |
QP10248-ec-5ug |
EnQuireBio |
5ug |
EUR 184.8 |
Recombinant Mouse CXCL1/ MGSA/ NAP-3 Protein, Untagged, E.coli-20ug |
QP10248-ec-20ug |
EnQuireBio |
20ug |
EUR 348 |
Recombinant Mouse CXCL1/ MGSA/ NAP-3 Protein, Untagged, E.coli-100ug |
QP10248-ec-100ug |
EnQuireBio |
100ug |
EUR 1185.6 |
Recombinant Mouse CXCL1/ MGSA/ NAP-3 Protein, Untagged, E.coli-250ug |
QP10248-ec-250ug |
EnQuireBio |
250ug |
EUR 2077.2 |
CLIA kit for Mouse GRO?/CXCL1 (Growth Regulated Oncogene Alpha) |
E-CL-M0017 |
Elabscience Biotech |
1 plate of 96 wells |
EUR 700.8 |
|
Description: A sandwich CLIA kit for quantitative measurement of Mouse GRO?/CXCL1 (Growth Regulated Oncogene Alpha) in samples from Serum, Plasma, Cell supernatant |
Cxcl1 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Mouse) |
K4368205 |
ABM |
3 x 1.0 ug |
EUR 451.2 |
ELISA kit for Mouse GRO?/CXCL1 (Growth Regulated Oncogene Alpha) |
E-EL-M0018 |
Elabscience Biotech |
1 plate of 96 wells |
EUR 640.8 |
|
Description: A sandwich ELISA kit for quantitative measurement of Mouse GRO?/CXCL1 (Growth Regulated Oncogene Alpha) in samples from Serum, Plasma, Cell supernatant |
Rat CXCL1 ELISA Kit |
55R-1742 |
Fitzgerald |
1 kit |
EUR 748.8 |
Description: ELISA kit for detection of CXCL1 in the research laboratory |
Polyclonal CXCL1 Antibody (C-Term) |
APG00617G |
Leading Biology |
0.1mg |
EUR 580.8 |
Description: A polyclonal antibody raised in Goat that recognizes and binds to Human CXCL1 (C-Term). This antibody is tested and proven to work in the following applications: |
Human CXCL1 ELISA Kit |
55R-1740 |
Fitzgerald |
1 kit |
EUR 748.8 |
Description: ELISA kit for detection of CXCL1 in the research laboratory |
CXCL1 protein (His tag) |
80R-2265 |
Fitzgerald |
100 ug |
EUR 508.8 |
Description: Purified recombinant Mouse CXCL1 Protein (His tag) |
Human CXCL1 ELISA Kit |
LF-EK50891 |
Abfrontier |
1×96T |
EUR 777.6 |
Dynamics of viral load and anti-SARS-CoV-2 antibodies in sufferers with constructive RT-PCR outcomes after restoration from COVID-19
The latest rise within the variety of coronavirus illness 2019 (COVID-19) sufferers examined as reverse transcription polymerase chain response (RT-PCR) constructive for extreme acute respiratory syndrome coronavirus 2 (SARS-CoV-2) after restoration has induced dilemma relating to the medical measures and polices. We evaluated the dynamics of viral load and anti-SARS-CoV-2 antibodies in four sufferers with constructive RT-PCR outcomes after restoration.
In all sufferers, IgG and IgM antibodies reached their most a couple of month after the onset of preliminary signs. Then, IgG titers plateaued, and IgM titers decreased no matter RT-PCR outcomes. The IgG and IgM antibodies didn’t rise after the positive-negative constructive RT-PCR leads to any of the sufferers. Our outcomes bolstered that the post-negative constructive RT-PCR outcomes could also be on account of detection of RNA particles somewhat than re-infection or recurrence in people who’ve recovered from COVID-19.
Antibody-Mediated Immune Subset Depletion Modulates the Immune Response in a Rabbit (Oryctolagus cuniculus) Mannequin of Epstein-Barr Virus An infection
- Epstein-Barr Virus (EBV) is a γ-herpesvirus which infects over 90% of the grownup human inhabitants. Most notably, this viruscauses infectious mononucleosis however additionally it is related with cancers resembling Hodgkin and Burkitt lymphoma. EBV is a species-specific virus and has been studied in lots of animal fashions, together with nonhuman primates, guinea pigs, humanized mice, and tree shrews.
- Nonetheless, none of those animal fashions are thought-about the “gold commonplace” for EBV analysis. Just lately, rabbits have emerged as a viable various mannequin, as they’re inclined to EBV an infection. As well as, the EBV an infection progresses after immune suppression with cyclosporine A (CsA), modeling the reactivation of EBV after latency. We sought to refine this mannequin for acute or energetic EBV infections by performing antibody-mediated depletion of sure immune subsets in rabbits.
- Fourteen 16 to 20-wk previous, NZW rabbits have been intravenously inoculated with EBV and concurrently handled with both anti-CD4 T-cell antibody, anti-pan-T-cell antibody (anti CD45), CSA, or, as a management, anti-HPV antibody.
- Rabbits that acquired the depleting antibodies have been handled with CsA three occasions at a dose of 15 mg/kg SC as soon as per day for four d beginning on the time of EBV inoculation then the dose was elevated to 20 mg/kg SC twice weekly for two wk. Weights, temperatures, and medical indicators have been monitored, and rabbits have been anesthetized as soon as weekly for blood assortment.
When put next with the management group, anti-CD4- handled rabbits had fewer medical indicators and displayed increased ranges of viral DNA by way of qPCR in splenocytes; nonetheless, circulation cytometry outcomes confirmed solely a partial depletion of CD4 T-cells. Therapy with anti-pan-T-cell antibody didn’t lead to noticeable T-cell depletion. These information recommend the EBV-infected rabbit is a promising mannequin for testing antiviral medicines and prophylactic vaccines for EBV.
Anti-Hu CD163 PE |
1P-645-T100 |
ExBio |
100 tests |
EUR 288 |
Anti-Hu CD163 APC |
1A-645-T025 |
ExBio |
25 tests |
EUR 168 |
Anti-Hu CD163 APC |
1A-645-T100 |
ExBio |
100 tests |
EUR 288 |
Anti-Hu CD163 Purified |
11-645-C025 |
ExBio |
0.025 mg |
EUR 118.8 |
Anti-Hu CD163 Purified |
11-645-C100 |
ExBio |
0.1 mg |
EUR 189.6 |
Human CD163 ELISA Kit |
LF-EK50890 |
Abfrontier |
1×96T |
EUR 777.6 |
Human CD163 shRNA Plasmid |
20-abx956176 |
Abbexa |
|
|
|
Anti-Hu CD163 PE-Cy7 |
T7-645-T025 |
ExBio |
25 tests |
EUR 184.8 |
Anti-Hu CD163 PE-Cy7 |
T7-645-T100 |
ExBio |
100 tests |
EUR 321.6 |
Anti-Hu CD163 PerCP-Cy5.5 |
T9-645-T025 |
ExBio |
25 tests |
EUR 235.2 |
Anti-Hu CD163 PerCP-Cy5.5 |
T9-645-T100 |
ExBio |
100 tests |
EUR 422.4 |
PE Anti-human CD163 Antibody *GHI/61* |
116301K0 |
AAT Bioquest |
25 tests |
EUR 383 |
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn |
PE Anti-human CD163 Antibody *GHI/61* |
116301K1 |
AAT Bioquest |
100 tests |
EUR 995 |
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn |
PE Anti-human CD163 Antibody *GHI/61* |
116301K2 |
AAT Bioquest |
500 tests |
EUR 2984 |
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn |
PE Anti-human CD163 Antibody *GHI/61* |
116301K0-25tests |
AAT Bioquest |
25 tests |
EUR 383 |
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen. |
PE Anti-human CD163 Antibody *GHI/61* |
116301K1-100tests |
AAT Bioquest |
100 tests |
EUR 995 |
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen. |
PE Anti-human CD163 Antibody *GHI/61* |
116301K2-500tests |
AAT Bioquest |
500 tests |
EUR 2984 |
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen. |
APC Anti-human CD163 Antibody *GHI/61* |
116301B0 |
AAT Bioquest |
25 tests |
EUR 383 |
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn |
APC Anti-human CD163 Antibody *GHI/61* |
116301B1 |
AAT Bioquest |
100 tests |
EUR 995 |
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn |
APC Anti-human CD163 Antibody *GHI/61* |
116301B2 |
AAT Bioquest |
500 tests |
EUR 2984 |
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn |
APC Anti-human CD163 Antibody *GHI/61* |
116301B0-25tests |
AAT Bioquest |
25 tests |
EUR 383 |
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen. |
APC Anti-human CD163 Antibody *GHI/61* |
116301B1-100tests |
AAT Bioquest |
100 tests |
EUR 995 |
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen. |
APC Anti-human CD163 Antibody *GHI/61* |
116301B2-500tests |
AAT Bioquest |
500 tests |
EUR 2984 |
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen. |
FITC Anti-human CD163 Antibody *GHI/61* |
116301G0 |
AAT Bioquest |
100 tests |
EUR 547 |
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn |
FITC Anti-human CD163 Antibody *GHI/61* |
116301G1 |
AAT Bioquest |
500 tests |
EUR 2051 |
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn |
FITC Anti-human CD163 Antibody *GHI/61* |
116301G0-100tests |
AAT Bioquest |
100 tests |
EUR 547 |
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen. |
FITC Anti-human CD163 Antibody *GHI/61* |
116301G1-500tests |
AAT Bioquest |
500 tests |
EUR 2051 |
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen. |
TRITC Anti-human CD163 Antibody *GHI/61* |
116301H0 |
AAT Bioquest |
100 tests |
EUR 547 |
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn |
TRITC Anti-human CD163 Antibody *GHI/61* |
116301H1 |
AAT Bioquest |
500 tests |
EUR 2051 |
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn |
PerCP Anti-human CD163 Antibody *GHI/61* |
116301S0 |
AAT Bioquest |
25 tests |
EUR 383 |
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn |
PerCP Anti-human CD163 Antibody *GHI/61* |
116301S1 |
AAT Bioquest |
100 tests |
EUR 995 |
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn |
PerCP Anti-human CD163 Antibody *GHI/61* |
116301S2 |
AAT Bioquest |
500 tests |
EUR 2984 |
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn |
TRITC Anti-human CD163 Antibody *GHI/61* |
116301H0-100tests |
AAT Bioquest |
100 tests |
EUR 547 |
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen. |
TRITC Anti-human CD163 Antibody *GHI/61* |
116301H1-500tests |
AAT Bioquest |
500 tests |
EUR 2051 |
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen. |
PerCP Anti-human CD163 Antibody *GHI/61* |
116301S0-25tests |
AAT Bioquest |
25 tests |
EUR 383 |
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen. |
PerCP Anti-human CD163 Antibody *GHI/61* |
116301S1-100tests |
AAT Bioquest |
100 tests |
EUR 995 |
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen. |
PerCP Anti-human CD163 Antibody *GHI/61* |
116301S2-500tests |
AAT Bioquest |
500 tests |
EUR 2984 |
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen. |
PacBlue Anti-human CD163 Antibody *GHI/61* |
116301I0 |
AAT Bioquest |
100 tests |
EUR 547 |
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn |
PacBlue Anti-human CD163 Antibody *GHI/61* |
116301I1 |
AAT Bioquest |
500 tests |
EUR 2051 |
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn |
PacBlue Anti-human CD163 Antibody *GHI/61* |
116301I0-100tests |
AAT Bioquest |
100 tests |
EUR 547 |
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen. |
PacBlue Anti-human CD163 Antibody *GHI/61* |
116301I1-500tests |
AAT Bioquest |
500 tests |
EUR 2051 |
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen. |
Purified Anti-human CD163 Antibody *GHI/61* |
11630000 |
AAT Bioquest |
100 ug |
EUR 365 |
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn |
Purified Anti-human CD163 Antibody *GHI/61* |
11630000-100ug |
AAT Bioquest |
100 ug |
EUR 365 |
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen. |
PacOrange Anti-human CD163 Antibody *GHI/61* |
116301J0 |
AAT Bioquest |
100 tests |
EUR 547 |
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn |
PacOrange Anti-human CD163 Antibody *GHI/61* |
116301J1 |
AAT Bioquest |
500 tests |
EUR 2051 |
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn |
PacOrange Anti-human CD163 Antibody *GHI/61* |
116301J0-100tests |
AAT Bioquest |
100 tests |
EUR 547 |
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen. |
PacOrange Anti-human CD163 Antibody *GHI/61* |
116301J1-500tests |
AAT Bioquest |
500 tests |
EUR 2051 |
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen. |
Human CellExp? CD163, Human recombinant |
9226-10 |
Biovision |
each |
EUR 366 |
Human CellExp? CD163, Human recombinant |
9226-50 |
Biovision |
each |
EUR 927.6 |
Canine CD163 antigen(CD163 LISA kit |
GA-E0062CN-48T |
GenAsia Biotech |
48T |
EUR 482.4 |
Canine CD163 antigen(CD163 LISA kit |
GA-E0062CN-96T |
GenAsia Biotech |
96T |
EUR 820.8 |
Porcine CD163 antigen,CD163 LISA kit |
GA-E0045PC-48T |
GenAsia Biotech |
48T |
EUR 436.8 |
Porcine CD163 antigen,CD163 LISA kit |
GA-E0045PC-96T |
GenAsia Biotech |
96T |
EUR 708 |
ELISA kit for Human CD163 |
EK5296 |
SAB |
96 tests |
EUR 663.6 |
Description: Enzyme-linked immunosorbent assay kit for quantification of Human CD163 in samples from serum, plasma, tissue homogenates and other biological fluids. |
Human CD163 PicoKine ELISA Kit |
EK0715 |
BosterBio |
96 wells |
EUR 510 |
Description: For quantitative detection of human CD163 in cell culture supernates, serum and plasma(heparin). |
CD163 Antibody |
20-abx242956 |
Abbexa |
|
|
|
CD163 antibody |
10R-6496 |
Fitzgerald |
100 ug |
EUR 243.6 |
Description: Mouse monoclonal CD163 antibody |
CD163 antibody |
10R-CD163aRT |
Fitzgerald |
250 ug |
EUR 859.2 |
Description: Mouse monoclonal CD163 antibody |
CD163 Antibody |
37157-100ul |
SAB |
100ul |
EUR 302.4 |
CD163 Antibody |
49553-100ul |
SAB |
100ul |
EUR 399.6 |
CD163 Antibody |
49553-50ul |
SAB |
50ul |
EUR 286.8 |
CD163 Antibody |
1-CSB-PA969205 |
Cusabio |
|
|
|
Description: A polyclonal antibody against CD163. Recognizes CD163 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:1000-1:2000, IHC:1:25-1:100 |
CD163 Antibody |
1-CSB-PA801238LA01HU |
Cusabio |
|
|
|
Description: A polyclonal antibody against CD163. Recognizes CD163 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IF; Recommended dilution: IF:1:50-1:200 |
Cd163 Antibody |
1-CSB-PA650452LA01MO |
Cusabio |
|
|
|
Description: A polyclonal antibody against Cd163. Recognizes Cd163 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB; Recommended dilution: WB:1:500-1:2000 |
CD163 Antibody |
F50316-0.4ML |
NSJ Bioreagents |
0.4 ml |
EUR 322.15 |
Description: CD163 is an acute phase-regulated receptor involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. The protein may play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. It binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH-dependent manner. And it exhibits a higher affinity for complexes of hemoglobin and multimeric haptoglobin of HP*1F phenotype than for complexes of hemoglobin and dimeric haptoglobin of HP*1S phenotype. It also induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1. |
CD163 Antibody |
F50316-0.08ML |
NSJ Bioreagents |
0.08 ml |
EUR 140.25 |
Description: CD163 is an acute phase-regulated receptor involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. The protein may play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. It binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH-dependent manner. And it exhibits a higher affinity for complexes of hemoglobin and multimeric haptoglobin of HP*1F phenotype than for complexes of hemoglobin and dimeric haptoglobin of HP*1S phenotype. It also induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1. |
CD163 Antibody |
RQ4259 |
NSJ Bioreagents |
100 ug |
EUR 356.15 |
Description: CD163 (Cluster of Differentiation 163) is a protein that in humans is encoded by the CD163 gene. The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
CD163 Antibody |
R30973 |
NSJ Bioreagents |
100 ug |
EUR 356.15 |
Description: CD163 (Cluster of Differentiation 163) is a human protein encoded by the CD163 gene. The receptor belongs to the scavenger receptor cysteine rich family type B and consists of an 1048 amino acid residues extracellular domain, a single transmembrane segment and a cytoplasmic tail with several splice variants. CD163 is a scavenger receptor for the hemoglobin-haptoglobincomplex. Using FISH, somatic cell hybrid analysis, and radiation hybrid analysis, Stover et al.(2000) mapped the CD163 gene to chromosome 12p13.3. Specific CD163-mediated endocytosis of haptoglobin-hemoglobin complexes was measurable in cells transfected with CD163 cDNA and in CD163-expressing myelomonocytic lymphoma cells.CD163 expression in monocytes promoted bacteria-induced proinflammatory cytokine production that could be blocked by anti-CD163 antibodies. Cells expressing human CD163 and recombinant protein containing the extracellular domain of CD163 supported adhesion of erythroblastic cells. |
CD163 Antibody |
R30974 |
NSJ Bioreagents |
100 ug |
EUR 356.15 |
Description: Cluster of Differentiation 163, also known as Hemoglobin scavenger receptor, is a human protein encoded by the CD163 gene. The receptor belongs to the scavenger receptor cysteine rich family type B and consists of an 1048 amino acid residues extracellular domain, a single transmembrane segment and a cytoplasmic tail with several splice variants. CD163 is a scavenger receptorfor the hemoglobin-haptoglobin complex. Using FISH, somatic cell hybrid analysis, and radiation hybrid analysis, Stover et al.(2000) mapped the gene to chromosome 12p13.3. CD163 expression in monocytes promoted bacteria-induced proinflammatory cytokine production that could be blocked by CD163 antibody. Cells expressing human CD163 and recombinant protein containing the extracellular domain of CD163 supported adhesion of erythroblastic cells. |
CD163 Antibody |
V3937-100UG |
NSJ Bioreagents |
100 ug |
EUR 349.3 |
Description: This antibody recognizes a protein of 140kDa, identified as CD163. It has been identified as an acute phase-regulated transmembrane protein whose function is to mediate the endocytosis of haptoglobin-hemoglobin complexes. This receptor is expressed on the surface of monocytes with low expression and on tissue macrophages, histiocytes with high expression. Staining with anti-CD163 has been helpful to distinguish synovial macrophages from synovial intimal fibroblasts in rheumatoid arthritis, where its specificity for macrophages was found to be superior to that of anti-CD68. Increased levels of CD163 were also detected in patients with microbial infections and myelomonocytic leukemias. Anti-CD163 is of considerable value for selective identification of monocytes and macrophages at a certain stage of differentiation and is suitable for diagnosing myelomonocytic or monocytic leukaemia and neoplasms of true histiocytic origin. CD163 is positive in skin (histiocytes), gut, Kupffer cells, a few alveolar macrophages, macrophages in the placenta, and in macrophages in inflamed tissues including tumor tissue. |
CD163 Antibody |
V3937-20UG |
NSJ Bioreagents |
20 ug |
EUR 153.3 |
Description: This antibody recognizes a protein of 140kDa, identified as CD163. It has been identified as an acute phase-regulated transmembrane protein whose function is to mediate the endocytosis of haptoglobin-hemoglobin complexes. This receptor is expressed on the surface of monocytes with low expression and on tissue macrophages, histiocytes with high expression. Staining with anti-CD163 has been helpful to distinguish synovial macrophages from synovial intimal fibroblasts in rheumatoid arthritis, where its specificity for macrophages was found to be superior to that of anti-CD68. Increased levels of CD163 were also detected in patients with microbial infections and myelomonocytic leukemias. Anti-CD163 is of considerable value for selective identification of monocytes and macrophages at a certain stage of differentiation and is suitable for diagnosing myelomonocytic or monocytic leukaemia and neoplasms of true histiocytic origin. CD163 is positive in skin (histiocytes), gut, Kupffer cells, a few alveolar macrophages, macrophages in the placenta, and in macrophages in inflamed tissues including tumor tissue. |
CD163 Antibody |
V3937SAF-100UG |
NSJ Bioreagents |
100 ug |
EUR 349.3 |
Description: This antibody recognizes a protein of 140kDa, identified as CD163. It has been identified as an acute phase-regulated transmembrane protein whose function is to mediate the endocytosis of haptoglobin-hemoglobin complexes. This receptor is expressed on the surface of monocytes with low expression and on tissue macrophages, histiocytes with high expression. Staining with anti-CD163 has been helpful to distinguish synovial macrophages from synovial intimal fibroblasts in rheumatoid arthritis, where its specificity for macrophages was found to be superior to that of anti-CD68. Increased levels of CD163 were also detected in patients with microbial infections and myelomonocytic leukemias. Anti-CD163 is of considerable value for selective identification of monocytes and macrophages at a certain stage of differentiation and is suitable for diagnosing myelomonocytic or monocytic leukaemia and neoplasms of true histiocytic origin. CD163 is positive in skin (histiocytes), gut, Kupffer cells, a few alveolar macrophages, macrophages in the placenta, and in macrophages in inflamed tissues including tumor tissue. |
CD163 Antibody |
V7470-100UG |
NSJ Bioreagents |
100 ug |
EUR 349.3 |
Description: This antibody recognizes a protein of 140kDa, identified as CD163. It has been identified as an acute phase-regulated transmembrane protein whose function is to mediate the endocytosis of haptoglobin-hemoglobin complexes. This receptor is expressed on the surface of monocytes with low expression and on tissue macrophages, histiocytes with high expression. Staining with anti-CD163 has been helpful to distinguish synovial macrophages from synovial intimal fibroblasts in rheumatoid arthritis, where its specificity for macrophages was found to be superior to that of anti-CD68. Increased levels of CD163 were also detected in patients with microbial infections and myelomonocytic leukemias. Anti-CD163 is of considerable value for selective identification of monocytes and macrophages at a certain stage of differentiation and is suitable for diagnosing myelomonocytic or monocytic leukaemia and neoplasms of true histiocytic origin. CD163 is positive in skin (histiocytes), gut, Kupffer cells, a few alveolar macrophages, macrophages in the placenta, and in macrophages in inflamed tissues including tumor tissue. |
CD163 Antibody |
V7470-20UG |
NSJ Bioreagents |
20 ug |
EUR 153.3 |
Description: This antibody recognizes a protein of 140kDa, identified as CD163. It has been identified as an acute phase-regulated transmembrane protein whose function is to mediate the endocytosis of haptoglobin-hemoglobin complexes. This receptor is expressed on the surface of monocytes with low expression and on tissue macrophages, histiocytes with high expression. Staining with anti-CD163 has been helpful to distinguish synovial macrophages from synovial intimal fibroblasts in rheumatoid arthritis, where its specificity for macrophages was found to be superior to that of anti-CD68. Increased levels of CD163 were also detected in patients with microbial infections and myelomonocytic leukemias. Anti-CD163 is of considerable value for selective identification of monocytes and macrophages at a certain stage of differentiation and is suitable for diagnosing myelomonocytic or monocytic leukaemia and neoplasms of true histiocytic origin. CD163 is positive in skin (histiocytes), gut, Kupffer cells, a few alveolar macrophages, macrophages in the placenta, and in macrophages in inflamed tissues including tumor tissue. |
CD163 Antibody |
V7470IHC-7ML |
NSJ Bioreagents |
7 ml |
EUR 349.3 |
Description: This antibody recognizes a protein of 140kDa, identified as CD163. It has been identified as an acute phase-regulated transmembrane protein whose function is to mediate the endocytosis of haptoglobin-hemoglobin complexes. This receptor is expressed on the surface of monocytes with low expression and on tissue macrophages, histiocytes with high expression. Staining with anti-CD163 has been helpful to distinguish synovial macrophages from synovial intimal fibroblasts in rheumatoid arthritis, where its specificity for macrophages was found to be superior to that of anti-CD68. Increased levels of CD163 were also detected in patients with microbial infections and myelomonocytic leukemias. Anti-CD163 is of considerable value for selective identification of monocytes and macrophages at a certain stage of differentiation and is suitable for diagnosing myelomonocytic or monocytic leukaemia and neoplasms of true histiocytic origin. CD163 is positive in skin (histiocytes), gut, Kupffer cells, a few alveolar macrophages, macrophages in the placenta, and in macrophages in inflamed tissues including tumor tissue. |
CD163 Antibody |
V7470SAF-100UG |
NSJ Bioreagents |
100 ug |
EUR 349.3 |
Description: This antibody recognizes a protein of 140kDa, identified as CD163. It has been identified as an acute phase-regulated transmembrane protein whose function is to mediate the endocytosis of haptoglobin-hemoglobin complexes. This receptor is expressed on the surface of monocytes with low expression and on tissue macrophages, histiocytes with high expression. Staining with anti-CD163 has been helpful to distinguish synovial macrophages from synovial intimal fibroblasts in rheumatoid arthritis, where its specificity for macrophages was found to be superior to that of anti-CD68. Increased levels of CD163 were also detected in patients with microbial infections and myelomonocytic leukemias. Anti-CD163 is of considerable value for selective identification of monocytes and macrophages at a certain stage of differentiation and is suitable for diagnosing myelomonocytic or monocytic leukaemia and neoplasms of true histiocytic origin. CD163 is positive in skin (histiocytes), gut, Kupffer cells, a few alveolar macrophages, macrophages in the placenta, and in macrophages in inflamed tissues including tumor tissue. |
CD163 Antibody |
V8227-100UG |
NSJ Bioreagents |
100 ug |
EUR 349.3 |
Description: This MAb recognizes a protein of 140kDa, identified as CD163. It has been identified as an acute phase-regulated transmembrane protein whose function is to mediate the endocytosis of haptoglobin-hemoglobin complexes. This receptor is expressed on the surface of monocytes with low expression and on tissue macrophages, histiocytes with high expression. Staining with anti-CD163 has been helpful to distinguish synovial macrophages from synovial intimal fibroblasts in rheumatoid arthritis, where its specificity for macrophages was found to be superior to that of anti-CD68. Increased levels of CD163 were also detected in patients with microbial infections and myelomonocytic leukemias. Anti-CD163 is of considerable value for selective identification of monocytes and macrophages at a certain stage of differentiation and is suitable for diagnosing myelomonocytic or monocytic leukaemia and neoplasms of true histiocytic origin. CD163 is positive in skin (histiocytes), gut, Kupffer cells, a few alveolar macrophages, macrophages in the placenta, and in macrophages in inflamed tissues including tumor tissue. |
CD163 Antibody |
V8227-20UG |
NSJ Bioreagents |
20 ug |
EUR 153.3 |
Description: This MAb recognizes a protein of 140kDa, identified as CD163. It has been identified as an acute phase-regulated transmembrane protein whose function is to mediate the endocytosis of haptoglobin-hemoglobin complexes. This receptor is expressed on the surface of monocytes with low expression and on tissue macrophages, histiocytes with high expression. Staining with anti-CD163 has been helpful to distinguish synovial macrophages from synovial intimal fibroblasts in rheumatoid arthritis, where its specificity for macrophages was found to be superior to that of anti-CD68. Increased levels of CD163 were also detected in patients with microbial infections and myelomonocytic leukemias. Anti-CD163 is of considerable value for selective identification of monocytes and macrophages at a certain stage of differentiation and is suitable for diagnosing myelomonocytic or monocytic leukaemia and neoplasms of true histiocytic origin. CD163 is positive in skin (histiocytes), gut, Kupffer cells, a few alveolar macrophages, macrophages in the placenta, and in macrophages in inflamed tissues including tumor tissue. |
CD163 Antibody |
V8227SAF-100UG |
NSJ Bioreagents |
100 ug |
EUR 349.3 |
Description: This MAb recognizes a protein of 140kDa, identified as CD163. It has been identified as an acute phase-regulated transmembrane protein whose function is to mediate the endocytosis of haptoglobin-hemoglobin complexes. This receptor is expressed on the surface of monocytes with low expression and on tissue macrophages, histiocytes with high expression. Staining with anti-CD163 has been helpful to distinguish synovial macrophages from synovial intimal fibroblasts in rheumatoid arthritis, where its specificity for macrophages was found to be superior to that of anti-CD68. Increased levels of CD163 were also detected in patients with microbial infections and myelomonocytic leukemias. Anti-CD163 is of considerable value for selective identification of monocytes and macrophages at a certain stage of differentiation and is suitable for diagnosing myelomonocytic or monocytic leukaemia and neoplasms of true histiocytic origin. CD163 is positive in skin (histiocytes), gut, Kupffer cells, a few alveolar macrophages, macrophages in the placenta, and in macrophages in inflamed tissues including tumor tissue. |
CD163 Antibody |
V8415-100UG |
NSJ Bioreagents |
100 ug |
EUR 349.3 |
Description: This MAb recognizes a protein of 140kDa, identified as CD163. It has been identified as an acute phase-regulated transmembrane protein whose function is to mediate the endocytosis of haptoglobin-hemoglobin complexes. This receptor is expressed on the surface of monocytes with low expression and on tissue macrophages, histiocytes with high expression. Staining with anti-CD163 has been helpful to distinguish synovial macrophages from synovial intimal fibroblasts in rheumatoid arthritis, where its specificity for macrophages was found to be superior to that of anti-CD68. Increased levels of CD163 were also detected in patients with microbial infections and myelomonocytic leukemias. Anti-CD163 is of considerable value for selective identification of monocytes and macrophages at a certain stage of differentiation and is suitable for diagnosing myelomonocytic or monocytic leukaemia and neoplasms of true histiocytic origin. CD163 is positive in skin (histiocytes), gut, Kupffer cells, a few alveolar macrophages, macrophages in the placenta, and in macrophages in inflamed tissues including tumor tissue. |
CD163 Antibody |
V8415-20UG |
NSJ Bioreagents |
20 ug |
EUR 153.3 |
Description: This MAb recognizes a protein of 140kDa, identified as CD163. It has been identified as an acute phase-regulated transmembrane protein whose function is to mediate the endocytosis of haptoglobin-hemoglobin complexes. This receptor is expressed on the surface of monocytes with low expression and on tissue macrophages, histiocytes with high expression. Staining with anti-CD163 has been helpful to distinguish synovial macrophages from synovial intimal fibroblasts in rheumatoid arthritis, where its specificity for macrophages was found to be superior to that of anti-CD68. Increased levels of CD163 were also detected in patients with microbial infections and myelomonocytic leukemias. Anti-CD163 is of considerable value for selective identification of monocytes and macrophages at a certain stage of differentiation and is suitable for diagnosing myelomonocytic or monocytic leukaemia and neoplasms of true histiocytic origin. CD163 is positive in skin (histiocytes), gut, Kupffer cells, a few alveolar macrophages, macrophages in the placenta, and in macrophages in inflamed tissues including tumor tissue. |
CD163 Antibody |
V8415SAF-100UG |
NSJ Bioreagents |
100 ug |
EUR 349.3 |
Description: This MAb recognizes a protein of 140kDa, identified as CD163. It has been identified as an acute phase-regulated transmembrane protein whose function is to mediate the endocytosis of haptoglobin-hemoglobin complexes. This receptor is expressed on the surface of monocytes with low expression and on tissue macrophages, histiocytes with high expression. Staining with anti-CD163 has been helpful to distinguish synovial macrophages from synovial intimal fibroblasts in rheumatoid arthritis, where its specificity for macrophages was found to be superior to that of anti-CD68. Increased levels of CD163 were also detected in patients with microbial infections and myelomonocytic leukemias. Anti-CD163 is of considerable value for selective identification of monocytes and macrophages at a certain stage of differentiation and is suitable for diagnosing myelomonocytic or monocytic leukaemia and neoplasms of true histiocytic origin. CD163 is positive in skin (histiocytes), gut, Kupffer cells, a few alveolar macrophages, macrophages in the placenta, and in macrophages in inflamed tissues including tumor tissue. |
CD163 Antibody |
V8757-100UG |
NSJ Bioreagents |
100 ug |
EUR 349.3 |
Description: CD163 is a type I membrane protein, and is a member of the hemoglobin scavenger receptor cystein-rich superfamily. The protein is involved in the clearance of hemoglobin-haptoglobin complexes and is considered to have anti-inflammatory functions. CD163 expression is restricted to the monocytic/macrophage lineage. It is expressed by all circulating monocytes and by a majority of tissue macrophages, such as splenic dendrocytes, alveolar macrophages and Kupffer cells of the liver. It is not present in macrophages in the mantle zone and some of the germinal center cells in lymph follicles, nor in Langerhans cells and interdigitating reticulum cells. In tumor tissues, CD163 is found in almost all cases of acute myeloid leukemia with monocytoid differentiation and in the majority of cases of histiocytic sarcoma, littoral cell angioma, Rosai-Dorfman disease, Langerhans cell histiocytosis and typical and atypical fibrous histiocytoma. It is also expressed in some cases of dermatofibrosarcoma protuberans. CD163 can be used to detect cells of monocytic and histiocyte lineage in neoplastic and reactive lesions. It has been shown to be more sensitive than CD68 for the detection of macrophages and monocytic cells. It covers a similar, but not identical, spectrum of cells as CD68. |
CD163 Antibody |
V8757-20UG |
NSJ Bioreagents |
20 ug |
EUR 153.3 |
Description: CD163 is a type I membrane protein, and is a member of the hemoglobin scavenger receptor cystein-rich superfamily. The protein is involved in the clearance of hemoglobin-haptoglobin complexes and is considered to have anti-inflammatory functions. CD163 expression is restricted to the monocytic/macrophage lineage. It is expressed by all circulating monocytes and by a majority of tissue macrophages, such as splenic dendrocytes, alveolar macrophages and Kupffer cells of the liver. It is not present in macrophages in the mantle zone and some of the germinal center cells in lymph follicles, nor in Langerhans cells and interdigitating reticulum cells. In tumor tissues, CD163 is found in almost all cases of acute myeloid leukemia with monocytoid differentiation and in the majority of cases of histiocytic sarcoma, littoral cell angioma, Rosai-Dorfman disease, Langerhans cell histiocytosis and typical and atypical fibrous histiocytoma. It is also expressed in some cases of dermatofibrosarcoma protuberans. CD163 can be used to detect cells of monocytic and histiocyte lineage in neoplastic and reactive lesions. It has been shown to be more sensitive than CD68 for the detection of macrophages and monocytic cells. It covers a similar, but not identical, spectrum of cells as CD68. |
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