Antibody-Mediated Immune Subset Depletion Modulates the Immune

Past Allotypes: The Affect of Allelic Variety in Antibody Fixed Domains

 

Polymorphic variety in antibody fixed domains has lengthy been outlined by allotypic motifs that cross react with the sera of different people. Enhancements in sequencing applied sciences have led to the invention of a lot of new allelic sequences that underlie this variety.

Most of the level mutations lie outdoors conventional allotypic motifs suggesting they don’t elicit immunogenic responses. As antibodies play an essential position in immune protection and biotechnology, understanding how this newly resolved variety influences the perform of antibodies is essential.

This overview investigates the present identified variety of antibody alleles at a protein stage for every antibody isotype in addition to the kappa and lambda mild chains.

We deal with proof rising for the way these mutations perturb antibody interactions with antigens and Fc receptors which are crucial for perform, as effectively because the affect this may need on the usage of antibodies as therapeutics and reagents.

toxhistory

toxhistory

GRO, KC, CXCL1, rRtGRO, rat

RC352-12 5ug
EUR 125.26

Mouse CXC-chemokine ligand 1(CXCL1/KC)ELISA Kit

YLA0122MO-48T 48T
EUR 465

Mouse CXC-chemokine ligand 1(CXCL1/KC)ELISA Kit

YLA0122MO-96T 96T
EUR 600

GRO/KC (CXCL1), Rat Recombinant

P1288-25 each
EUR 444

GRO/KC (CXCL1), Rat Recombinant

P1288-5 each
EUR 210

Recombinant Murine KC (CXCL1) Protein

PROTP12850-2 20ug
EUR 380.4
Description: All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. Recombinant murine KC is a 7.8 kDa protein consisting of 72 amino acids including the 'ELR' motif common to the CXC chemokine family that bind to CXCR1 or CXCR2.

Recombinant Rat GRO/KC (CXCL1) Protein

PROTP14095-1 25ug
EUR 380.4
Description: All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. Recombinant rat GRO/KC is a 7.8 kDa protein consisting of 72 amino acids including the 'ELR' motif common to the CXC chemokine family that bind to CXCR1 or CXCR2.

Rat CXCL1/CINC-1/KC ELISA Kit

RK00196 96 Tests
EUR 625.2

Rabbit Anti Mouse Cxcl1 Polyclonal Antibody

CPBT-65100RM 0.1 mg
EUR 1057.2

Mouse CXCL1 ELISA Kit

55R-1741 1 kit
EUR 748.8
Description: ELISA kit for detection of CXCL1 in the research laboratory

Mouse CXCL1 shRNA Plasmid

20-abx970673
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

GRO-alpha/CXCL1, Mouse

HY-P7188 50ug
EUR 639.6

ELISA kit for Mouse CXCL1

EK5299 96 tests
EUR 663.6
Description: Enzyme-linked immunosorbent assay kit for quantification of Mouse CXCL1 in samples from serum, plasma, tissue homogenates and other biological fluids.

Mouse CXCL1/GROα ELISA kit

LF-EK50473 1×96T
EUR 777.6

Mouse CXCL1 PicoKine ELISA Kit

EK0723 96 wells
EUR 547.2
Description: For quantitative detection of mouse CXCL1 in cell culture supernates and serum.

Mouse CXCL1 Detection Assay Kit

6725 1 kit
EUR 580.26
Description: Mouse CXCL1 Detection Assay Kit

CXCL1 protein (Mouse) (His tag)

80R-3368 50 ug
EUR 308.4
Description: Purified recombinant CXCL1 protein (Mouse) (His tag)

CXCL1 protein (Mouse) (His tag)

80R-3439 50 ug
EUR 308.4
Description: Purified recombinant CXCL1 protein (Mouse) (His tag)

Cxcl1 ORF Vector (Mouse) (pORF)

ORF042286 1.0 ug DNA
EUR 114

Mouse CXCL1 AssayLite Antibody (FITC Conjugate)

70027-05141 150 ug
EUR 513.6

CXCL1 ELISA Kit (Mouse) (OKBB00312)

OKBB00312 96 Tests
EUR 652.8
Description: Description of target: Chemokine (C-X-C motif) ligand 1 (CXCL1) is a small cytokine belonging to the CXC chemokine family that was previously called GRO1 oncogene, GROα, KC, Neutrophil-activating protein 3 (NAP-3) and melanoma growth stimulating activity, alpha (MSGA-α). In humans, this protein is encoded by the CXCL1 gene. The gene for CXCL1 is located on human chromosome 4 amongst genes for other CXC chemokines. The mature form of CXCL1 is maximally 73 amino acids long. CXCL1 is secreted by human melanoma cells, has mitogenic properties and is implicated in melanoma pathogenesis. CXCL1 is expressed by macrophages, neutrophils and epithelial cells, and has neutrophil chemoattractant activity. This chemokine elicits its effects by signaling through the chemokine receptor CXCR2.CXCL1 decreased the severity of multiple sclerosis and may offer a neuro-protective function. The standard product used in this kit is recombinant mouse CXCL1, consisting of 77 amino acids with the molecular mass of 8KDa.;Species reactivity: Mouse;Application: ELISA;Assay info: ;Sensitivity: < 1 pg/ml

CXCL1 ELISA Kit (Mouse) (OKAN04583)

OKAN04583 96 Wells
EUR 950.4
Description: Description of target: This gene encodes a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This secretory protein is proposed to bind the G-protein coupled receptor chemokine (C-X-C motif) receptor 2 to recruit neutrophils. In mouse, deficiency of this gene is associated with colitis and with defects in immune cell recruitment to the lung.;Species reactivity: Mouse;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 6.0 pg/mL

CXCL1 ELISA Kit (Mouse) (OKCD05712)

OKCD05712 96 Wells
EUR 730.8
Description: Description of target: This gene encodes a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This secretory protein is proposed to bind the G-protein coupled receptor chemokine (C-X-C motif) receptor 2 to recruit neutrophils. In mouse, deficiency of this gene is associated with colitis and with defects in immune cell recruitment to the lung.;Species reactivity: Mouse;Application: ELISA;Assay info: ;Sensitivity: < 6.0pg/mL

Mouse CXCL1/GROα ELISA kit (4X96T)

LF-EK50474 4×96T
EUR 2641.2

Anti-GRO alpha/Cxcl1 Antibody

A00533 100ug/vial
EUR 352.8

Anti-GRO alpha/CXCL1 Antibody

PA1760 100ug/vial
EUR 352.8

CXCL1 Antibody

43679-100ul 100ul
EUR 302.4

CXCL1 antibody

70R-10502 50 ug
EUR 560.4
Description: Affinity purified rabbit polyclonal CXCL1 antibody

CXCL1 antibody

70R-14297 100 ug
EUR 392.4
Description: Affinity purified Rabbit polyclonal CXCL1 antibody

CXCL1 antibody

70R-16681 50 ul
EUR 522
Description: Rabbit polyclonal CXCL1 antibody

CXCL1 antibody

70R-15473 100 ug
EUR 392.4
Description: Rabbit polyclonal CXCL1 antibody

CXCL1 Antibody

33054-100ul 100ul
EUR 302.4

CXCL1 Antibody

1-CSB-PA006239GA01HU
  • EUR 716.40
  • EUR 399.60
  • 150ul
  • 50ul
Description: A polyclonal antibody against CXCL1. Recognizes CXCL1 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC

CXCL1 Antibody

1-CSB-PA06097A0Rb
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against CXCL1. Recognizes CXCL1 from Human. This antibody is Unconjugated. Tested in the following application: ELISA

CXCL1 Antibody

1-CSB-PA009036
  • EUR 266.40
  • EUR 234.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against CXCL1. Recognizes CXCL1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: IHC, ELISA;IHC:1/100-1/300.ELISA:1/10000

Cxcl1 Antibody

1-CSB-PA09217A0Rb
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against Cxcl1. Recognizes Cxcl1 from Mouse. This antibody is Unconjugated. Tested in the following application: ELISA

GRO-alpha/CXCL1 (CHO-expressed), Mouse

HY-P7186 50ug
EUR 404.4

Cxcl1 sgRNA CRISPR Lentivector set (Mouse)

K4368201 3 x 1.0 ug
EUR 406.8

Mouse Growth-regulated alpha protein (Cxcl1)

1-CSB-RP092174m
  • EUR 606.00
  • EUR 318.00
  • EUR 2192.40
  • EUR 919.20
  • EUR 1461.60
  • EUR 402.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Mouse Growth-regulated alpha protein(Cxcl1),partial expressed in E.coli

CXCL1 Protein Vector (Mouse) (pPM-C-HA)

PV169144 500 ng
EUR 723.6

Cxcl1 ELISA Kit (Mouse) : 96 Wells (OKEH02714)

OKEH02714 96 Wells
EUR 652.8
Description: Description of target: This gene encodes a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This secretory protein is proposed to bind the G-protein coupled receptor chemokine (C-X-C motif) receptor 2 to recruit neutrophils. In mouse, deficiency of this gene is associated with colitis and with defects in immune cell recruitment to the lung. ;Species reactivity: Mouse;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 15.76 pg/mL

CXCL1 Protein Vector (Mouse) (pPB-C-His)

PV169142 500 ng
EUR 723.6

CXCL1 Protein Vector (Mouse) (pPB-N-His)

PV169143 500 ng
EUR 723.6

CXCL1 Protein Vector (Mouse) (pPM-C-His)

PV169145 500 ng
EUR 723.6

Nori® Mouse CXCL1/GRO-alpha ELISA Kit

GR117324 96-well
EUR 461

CXCL1 antibody (HRP)

60R-2236 100 ug
EUR 392.4
Description: Rabbit polyclonal CXCL1 antibody (HRP)

Rabbit Anti Rat Cxcl1 Polyclonal Antibody

CPBT-65101RR 0.1 mg
EUR 1057.2

CXCL1 antibody (FITC)

60R-2237 100 ug
EUR 392.4
Description: Rabbit polyclonal CXCL1 antibody (FITC)

CXCL1/GRO

EF012822 96 Tests
EUR 826.8

CXCL1/GRO

E21-597 10ug
EUR 411.6

Cxcl1 sgRNA CRISPR Lentivector (Mouse) (Target 1)

K4368202 1.0 ug DNA
EUR 184.8

Cxcl1 sgRNA CRISPR Lentivector (Mouse) (Target 2)

K4368203 1.0 ug DNA
EUR 184.8

Cxcl1 sgRNA CRISPR Lentivector (Mouse) (Target 3)

K4368204 1.0 ug DNA
EUR 184.8

CXCL1 antibody (biotin)

60R-2238 100 ug
EUR 392.4
Description: Rabbit polyclonal CXCL1 antibody (biotin)

CXCL1 siRNA

20-abx913248
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

CXCL1 siRNA

20-abx913249
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

CXCL1 siRNA

20-abx901350
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

pEGFP- CXCL1

PVT10178 2 ug
EUR 361.2

CXCL1 protein

30R-3156 50 ug
EUR 308.4
Description: Purified recombinant CXCL1 protein

CXCL1 Peptide

42-129P 0.1 mg
EUR 405.6
Description: (CT) CXCL1 Peptide

CXCL1 Conjugated Antibody

C33054 100ul
EUR 476.4

Cxcl1 Polyclonal Antibody

A51950
  • EUR 684.66
  • EUR 117.70
  • EUR 302.50
  • EUR 423.50
  • 100 µg
  • 20 ul
  • 50 ul
  • 100 ul

CXCL1 Polyclonal Antibody

A51978
  • EUR 684.66
  • EUR 117.70
  • EUR 302.50
  • EUR 423.50
  • 100 µg
  • 20 ul
  • 50 ul
  • 100 ul

CXCL1 Chemi-Luminescent ELISA Kit (Mouse) (OKCD03823)

OKCD03823 96 Wells
EUR 1232.4
Description: Description of target: Has chemotactic activity for neutrophils. Contributes to neutrophil activation during inflammation . Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. KC(5-72) shows a highly enhanced hematopoietic activity.;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 15.6 pg/mL

Mouse Cxcl1/ Growth-regulated alpha protein ELISA Kit

E0354Mo 1 Kit
EUR 655.2

Mouse Growth regulated alpha protein, Cxcl1 ELISA KIT

ELI-04012m 96 Tests
EUR 1038

GRO alpha (CXCL1) Antibody

abx018005-100ug 100 ug
EUR 410.4

Gro alpha Antibody / CXCL1

RQ4031 100 ug
EUR 356.15
Description: CXCL1 (Chemokine, CXC motif, Ligand 1), also called GRO1, SCYB1, GROA or MGSA, is a small cytokine belonging to the CXC chemokine family that was previously called GRO1 oncogene, GRO?, KC, Neutrophil-activating protein 3 (NAP-3) and melanoma growth stimulating activity, alpha (MSGA-?). In humans, this protein is encoded by the CXCL1 gene. The CXCL1 gene is mapped on 4q13.3. CXCL1 is secreted by human melanoma cells, has mitogenic properties and is implicated in melanoma pathogenesis. It is expressed by macrophages, neutrophils and epithelial cells, and has neutrophil chemoattractant activity. CXCL1 plays a role in spinal cord development by inhibiting the migration of oligodendrocyte precursors and is involved in the processes of angiogenesis, inflammation, wound healing, and tumorigenesis. Signaling through Cxcr2, Cxcl1 inhibited oligodendrocyte precursor migration. The migrational arrest was rapid, reversible, and concentration dependent, and it reflected enhanced cell/substrate interactions. White matter expression of Cxcl1 was temporospatially regulated. Others contribute to aggressive growth selectivity in the lung. Among the lung metastasis signature genes identified, several, including CXCL1, were functionally validated.

Mouse Growth-Regulated Alpha Protein (CXCL1) ELISA Kit

abx253956-96tests 96 tests
EUR 801.6

Mouse Growth-Regulated Alpha Protein (CXCL1) ELISA Kit

20-abx154438
  • EUR 6373.20
  • EUR 3404.40
  • EUR 801.60
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Mouse Growth-Regulated Alpha Protein (CXCL1) ELISA Kit

abx050043-96tests 96 tests
EUR 924

Mouse Growth-Regulated Alpha Protein (CXCL1) ELISA Kit

abx574645-96tests 96 tests
EUR 801.6

Mouse CXCL1/GROα(Growth Regulated Oncogene Alpha) ELISA Kit

EM0003 96T
EUR 571.5
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 9.375pg/ml

CXCL1 Antibody, HRP conjugated

1-CSB-PA06097B0Rb
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against CXCL1. Recognizes CXCL1 from Human. This antibody is HRP conjugated. Tested in the following application: ELISA

Cxcl1 Antibody, HRP conjugated

1-CSB-PA09217B0Rb
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against Cxcl1. Recognizes Cxcl1 from Mouse. This antibody is HRP conjugated. Tested in the following application: ELISA

CXCL1 Antibody, FITC conjugated

1-CSB-PA06097C0Rb
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against CXCL1. Recognizes CXCL1 from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

Cxcl1 Antibody, FITC conjugated

1-CSB-PA09217C0Rb
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against Cxcl1. Recognizes Cxcl1 from Mouse. This antibody is FITC conjugated. Tested in the following application: ELISA

CXCL1 Antibody, Biotin conjugated

1-CSB-PA06097D0Rb
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against CXCL1. Recognizes CXCL1 from Human. This antibody is Biotin conjugated. Tested in the following application: ELISA

Cxcl1 Antibody, Biotin conjugated

1-CSB-PA09217D0Rb
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against Cxcl1. Recognizes Cxcl1 from Mouse. This antibody is Biotin conjugated. Tested in the following application: ELISA

Recombinant Mouse CXCL1/ GRO-alpha Protein, Untagged, E.coli-1mg

QP1455-1mg 1mg
EUR 3427.2

Recombinant Mouse CXCL1/ GRO-alpha Protein, Untagged, E.coli-5ug

QP1455-5ug 5ug
EUR 163.2

Recombinant Mouse CXCL1/ GRO-alpha Protein, Untagged, E.coli-20ug

QP1455-20ug 20ug
EUR 284.4

Mouse Growth Regulated Oncogene Alpha / GROa (CXCL1) CLIA Kit

abx196070-96tests 96 tests
EUR 990

CXCL1 cloning plasmid

CSB-CL006239HU-10ug 10ug
EUR 279.6
Description: A cloning plasmid for the CXCL1 gene.

Recombinant Mouse CXCL1/ MGSA/ NAP-3 Protein, His, E.coli-1mg

QP8650-ec-1mg 1mg
EUR 2763.6

Recombinant Mouse CXCL1/ GRO-alpha Protein, Untagged, E.coli-100ug

QP1455-100ug 100ug
EUR 588

Recombinant Mouse CXCL1/ GRO-alpha Protein, Untagged, E.coli-500ug

QP1455-500ug 500ug
EUR 2133.6

CXCL1 Blocking Peptide

20-abx061039
  • EUR 343.20
  • EUR 510.00
  • 1 mg
  • 5 mg

CXCL1 Blocking Peptide

33R-7741 100 ug
EUR 216
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of CXCL1 antibody, catalog no. 70R-10502

Recombinant Mouse CXCL1/ MGSA/ NAP-3 Protein, His, E.coli-10ug

QP8650-ec-10ug 10ug
EUR 326.4

Recombinant Mouse CXCL1/ MGSA/ NAP-3 Protein, His, E.coli-50ug

QP8650-ec-50ug 50ug
EUR 434.4

Recombinant Human CXCL1

P0109 100ug
EUR 626.83
Description: Recombinant Human protein for CXCL1

Recombinant Human CXCL1

P0207 100ug
EUR 626.83
Description: Recombinant Human protein for CXCL1

Recombinant Mouse CXCL1/ MGSA/ NAP-3 Protein, His, E.coli-100ug

QP8650-ec-100ug 100ug
EUR 685.2

Recombinant Mouse CXCL1/ MGSA/ NAP-3 Protein, His, E.coli-200ug

QP8650-ec-200ug 200ug
EUR 1077.6

Recombinant Mouse CXCL1/ MGSA/ NAP-3 Protein, His, E.coli-500ug

QP8650-ec-500ug 500ug
EUR 1816.8

CXCL1 Recombinant Protein

91-532 0.05 mg
EUR 714.3
Description: Chemokine (C-X-C motif) Ligand 1 Protein (CXCL1) is a growth factor for melanoma cells and a chemotaxin for neutrophils and a member of the CXC chemokine family that is a potent neutrophil attractant and activator and is also active toward basophils. CXCL1 is expressed by macrophages, neutrophils and epithelial cells; it has neutrophil chemoattractant activity. CXCL1 plays a critical nonredundant role in the development of experimental Lyme arthritis and carditis via CXCR2-mediated recruitment of neutrophils into the site of infection and may also have important pro-nociceptive effects via its direct actions on sensory neurons, and may induce long-term changes that involve protein synthesis.

CXCL1 Recombinant Protein

91-628 0.05 mg
EUR 651.3
Description: Cxcl1, also called Gro, Gro1, Mgsa or Scyb1, is short for growth-regulated alpha protein. The protein belongs to the intercrine alpha (chemokine CxC) family. The N-terminal processed form KC(5-72) of the protein is produced by proteolytic cleavage after secretion from bone marrow stromal cells, and shows a highly enhanced hematopoietic activity. Cxcl1 has chemotactic activity for neutrophils, and contributes to neutrophil activation during inflammation. Hematoregulatory chemokine, in vitro, suppresses hematopoietic progenitor cell proliferation.

Recombinant Mouse CXCL1/ MGSA/ NAP-3 Protein, Untagged, E.coli-5ug

QP10248-ec-5ug 5ug
EUR 184.8

Recombinant Mouse CXCL1/ MGSA/ NAP-3 Protein, Untagged, E.coli-20ug

QP10248-ec-20ug 20ug
EUR 348

Recombinant Mouse CXCL1/ MGSA/ NAP-3 Protein, Untagged, E.coli-100ug

QP10248-ec-100ug 100ug
EUR 1185.6

Recombinant Mouse CXCL1/ MGSA/ NAP-3 Protein, Untagged, E.coli-250ug

QP10248-ec-250ug 250ug
EUR 2077.2

CLIA kit for Mouse GRO?/CXCL1 (Growth Regulated Oncogene Alpha)

E-CL-M0017 1 plate of 96 wells
EUR 700.8
Description: A sandwich CLIA kit for quantitative measurement of Mouse GRO?/CXCL1 (Growth Regulated Oncogene Alpha) in samples from Serum, Plasma, Cell supernatant

Cxcl1 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Mouse)

K4368205 3 x 1.0 ug
EUR 451.2

ELISA kit for Mouse GRO?/CXCL1 (Growth Regulated Oncogene Alpha)

E-EL-M0018 1 plate of 96 wells
EUR 640.8
Description: A sandwich ELISA kit for quantitative measurement of Mouse GRO?/CXCL1 (Growth Regulated Oncogene Alpha) in samples from Serum, Plasma, Cell supernatant

Rat CXCL1 ELISA Kit

55R-1742 1 kit
EUR 748.8
Description: ELISA kit for detection of CXCL1 in the research laboratory

Polyclonal CXCL1 Antibody (C-Term)

APG00617G 0.1mg
EUR 580.8
Description: A polyclonal antibody raised in Goat that recognizes and binds to Human CXCL1 (C-Term). This antibody is tested and proven to work in the following applications:

Human CXCL1 ELISA Kit

55R-1740 1 kit
EUR 748.8
Description: ELISA kit for detection of CXCL1 in the research laboratory

CXCL1 protein (His tag)

80R-2265 100 ug
EUR 508.8
Description: Purified recombinant Mouse CXCL1 Protein (His tag)

Human CXCL1 ELISA Kit

LF-EK50891 1×96T
EUR 777.6

 

Dynamics of viral load and anti-SARS-CoV-2 antibodies in sufferers with constructive RT-PCR outcomes after restoration from COVID-19

The latest rise within the variety of coronavirus illness 2019 (COVID-19) sufferers examined as reverse transcription polymerase chain response (RT-PCR) constructive for extreme acute respiratory syndrome coronavirus 2 (SARS-CoV-2) after restoration has induced dilemma relating to the medical measures and polices. We evaluated the dynamics of viral load and anti-SARS-CoV-2 antibodies in four sufferers with constructive RT-PCR outcomes after restoration.

In all sufferers, IgG and IgM antibodies reached their most a couple of month after the onset of preliminary signs. Then, IgG titers plateaued, and IgM titers decreased no matter RT-PCR outcomes. The IgG and IgM antibodies didn’t rise after the positive-negative constructive RT-PCR leads to any of the sufferers. Our outcomes bolstered that the post-negative constructive RT-PCR outcomes could also be on account of detection of RNA particles somewhat than re-infection or recurrence in people who’ve recovered from COVID-19.

 

Antibody-Mediated Immune Subset Depletion Modulates the Immune Response in a Rabbit (Oryctolagus cuniculus) Mannequin of Epstein-Barr Virus An infection

  • Epstein-Barr Virus (EBV) is a γ-herpesvirus which infects over 90% of the grownup human inhabitants. Most notably, this viruscauses infectious mononucleosis however additionally it is related with cancers resembling Hodgkin and Burkitt lymphoma. EBV is a species-specific virus and has been studied in lots of animal fashions, together with nonhuman primates, guinea pigs, humanized mice, and tree shrews.
  • Nonetheless, none of those animal fashions are thought-about the “gold commonplace” for EBV analysis. Just lately, rabbits have emerged as a viable various mannequin, as they’re inclined to EBV an infection. As well as, the EBV an infection progresses after immune suppression with cyclosporine A (CsA), modeling the reactivation of EBV after latency. We sought to refine this mannequin for acute or energetic EBV infections by performing antibody-mediated depletion of sure immune subsets in rabbits.
  • Fourteen 16 to 20-wk previous, NZW rabbits have been intravenously inoculated with EBV and concurrently handled with both anti-CD4 T-cell antibody, anti-pan-T-cell antibody (anti CD45), CSA, or, as a management, anti-HPV antibody.
  • Rabbits that acquired the depleting antibodies have been handled with CsA three occasions at a dose of 15 mg/kg SC as soon as per day for four d beginning on the time of EBV inoculation then the dose was elevated to 20 mg/kg SC twice weekly for two wk. Weights, temperatures, and medical indicators have been monitored, and rabbits have been anesthetized as soon as weekly for blood assortment.

When put next with the management group, anti-CD4- handled rabbits had fewer medical indicators and displayed increased ranges of viral DNA by way of qPCR in splenocytes; nonetheless, circulation cytometry outcomes confirmed solely a partial depletion of CD4 T-cells. Therapy with anti-pan-T-cell antibody didn’t lead to noticeable T-cell depletion. These information recommend the EBV-infected rabbit is a promising mannequin for testing antiviral medicines and prophylactic vaccines for EBV.

 

 

Anti-Hu CD163 PE

1P-645-T100 100 tests
EUR 288

Anti-Hu CD163 APC

1A-645-T025 25 tests
EUR 168

Anti-Hu CD163 APC

1A-645-T100 100 tests
EUR 288

Anti-Hu CD163 Purified

11-645-C025 0.025 mg
EUR 118.8

Anti-Hu CD163 Purified

11-645-C100 0.1 mg
EUR 189.6

Human CD163 ELISA Kit

LF-EK50890 1×96T
EUR 777.6

Human CD163 ELISA Kit

ELA-E1726h 96 Tests
EUR 988.8

Human CD163 shRNA Plasmid

20-abx956176
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

Anti-Hu CD163 PE-Cy7

T7-645-T025 25 tests
EUR 184.8

Anti-Hu CD163 PE-Cy7

T7-645-T100 100 tests
EUR 321.6

Anti-Hu CD163 PerCP-Cy5.5

T9-645-T025 25 tests
EUR 235.2

Anti-Hu CD163 PerCP-Cy5.5

T9-645-T100 100 tests
EUR 422.4

PE Anti-human CD163 Antibody *GHI/61*

116301K0 25 tests
EUR 383
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn

PE Anti-human CD163 Antibody *GHI/61*

116301K1 100 tests
EUR 995
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn

PE Anti-human CD163 Antibody *GHI/61*

116301K2 500 tests
EUR 2984
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn

PE Anti-human CD163 Antibody *GHI/61*

116301K0-25tests 25 tests
EUR 383
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PE Anti-human CD163 Antibody *GHI/61*

116301K1-100tests 100 tests
EUR 995
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PE Anti-human CD163 Antibody *GHI/61*

116301K2-500tests 500 tests
EUR 2984
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

APC Anti-human CD163 Antibody *GHI/61*

116301B0 25 tests
EUR 383
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn

APC Anti-human CD163 Antibody *GHI/61*

116301B1 100 tests
EUR 995
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn

APC Anti-human CD163 Antibody *GHI/61*

116301B2 500 tests
EUR 2984
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn

APC Anti-human CD163 Antibody *GHI/61*

116301B0-25tests 25 tests
EUR 383
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

APC Anti-human CD163 Antibody *GHI/61*

116301B1-100tests 100 tests
EUR 995
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

APC Anti-human CD163 Antibody *GHI/61*

116301B2-500tests 500 tests
EUR 2984
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

FITC Anti-human CD163 Antibody *GHI/61*

116301G0 100 tests
EUR 547
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn

FITC Anti-human CD163 Antibody *GHI/61*

116301G1 500 tests
EUR 2051
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn

FITC Anti-human CD163 Antibody *GHI/61*

116301G0-100tests 100 tests
EUR 547
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

FITC Anti-human CD163 Antibody *GHI/61*

116301G1-500tests 500 tests
EUR 2051
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

TRITC Anti-human CD163 Antibody *GHI/61*

116301H0 100 tests
EUR 547
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn

TRITC Anti-human CD163 Antibody *GHI/61*

116301H1 500 tests
EUR 2051
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn

PerCP Anti-human CD163 Antibody *GHI/61*

116301S0 25 tests
EUR 383
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn

PerCP Anti-human CD163 Antibody *GHI/61*

116301S1 100 tests
EUR 995
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn

PerCP Anti-human CD163 Antibody *GHI/61*

116301S2 500 tests
EUR 2984
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn

TRITC Anti-human CD163 Antibody *GHI/61*

116301H0-100tests 100 tests
EUR 547
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

TRITC Anti-human CD163 Antibody *GHI/61*

116301H1-500tests 500 tests
EUR 2051
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PerCP Anti-human CD163 Antibody *GHI/61*

116301S0-25tests 25 tests
EUR 383
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PerCP Anti-human CD163 Antibody *GHI/61*

116301S1-100tests 100 tests
EUR 995
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PerCP Anti-human CD163 Antibody *GHI/61*

116301S2-500tests 500 tests
EUR 2984
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PacBlue Anti-human CD163 Antibody *GHI/61*

116301I0 100 tests
EUR 547
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn

PacBlue Anti-human CD163 Antibody *GHI/61*

116301I1 500 tests
EUR 2051
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn

PacBlue Anti-human CD163 Antibody *GHI/61*

116301I0-100tests 100 tests
EUR 547
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PacBlue Anti-human CD163 Antibody *GHI/61*

116301I1-500tests 500 tests
EUR 2051
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

Purified Anti-human CD163 Antibody *GHI/61*

11630000 100 ug
EUR 365
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn

Purified Anti-human CD163 Antibody *GHI/61*

11630000-100ug 100 ug
EUR 365
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PacOrange Anti-human CD163 Antibody *GHI/61*

116301J0 100 tests
EUR 547
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn

PacOrange Anti-human CD163 Antibody *GHI/61*

116301J1 500 tests
EUR 2051
Description: R-Phrase for Dangerous Goods accord. to EU 67/548 EWG: R20, R21, R22; H-Phrases (GHS) for Dangerous Goods accord. to 1272/2008: H303, H313, H333; Symbol for Dangerous Compound accord. to EU 67/548 EWG: Xn

PacOrange Anti-human CD163 Antibody *GHI/61*

116301J0-100tests 100 tests
EUR 547
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PacOrange Anti-human CD163 Antibody *GHI/61*

116301J1-500tests 500 tests
EUR 2051
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

Human CellExp? CD163, Human recombinant

9226-10 each
EUR 366

Human CellExp? CD163, Human recombinant

9226-50 each
EUR 927.6

Canine CD163 antigen(CD163 LISA kit

GA-E0062CN-48T 48T
EUR 482.4

Canine CD163 antigen(CD163 LISA kit

GA-E0062CN-96T 96T
EUR 820.8

Porcine CD163 antigen,CD163 LISA kit

GA-E0045PC-48T 48T
EUR 436.8

Porcine CD163 antigen,CD163 LISA kit

GA-E0045PC-96T 96T
EUR 708

Porcine CD163 antigen,CD163 LISA kit

YLA0139PO-48T 48T
EUR 502.5

Porcine CD163 antigen,CD163 LISA kit

YLA0139PO-96T 96T
EUR 618.75

ELISA kit for Human CD163

EK5296 96 tests
EUR 663.6
Description: Enzyme-linked immunosorbent assay kit for quantification of Human CD163 in samples from serum, plasma, tissue homogenates and other biological fluids.

Human CD163 PicoKine ELISA Kit

EK0715 96 wells
EUR 510
Description: For quantitative detection of human CD163 in cell culture supernates, serum and plasma(heparin).

CD163 Antibody

20-abx242956
  • EUR 560.40
  • EUR 393.60
  • 100 ul
  • 50 ul

CD163 antibody

10R-6496 100 ug
EUR 243.6
Description: Mouse monoclonal CD163 antibody

CD163 antibody

10R-CD163aRT 250 ug
EUR 859.2
Description: Mouse monoclonal CD163 antibody

CD163 Antibody

37157-100ul 100ul
EUR 302.4

CD163 Antibody

49553-100ul 100ul
EUR 399.6

CD163 Antibody

49553-50ul 50ul
EUR 286.8

CD163 Antibody

ABD8235 100 ug
EUR 525.6

CD163 Antibody

DF8235 200ul
EUR 420

CD163 Antibody

1-CSB-PA969205
  • EUR 380.40
  • EUR 292.80
  • 100ul
  • 50ul
Description: A polyclonal antibody against CD163. Recognizes CD163 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:1000-1:2000, IHC:1:25-1:100

CD163 Antibody

1-CSB-PA801238LA01HU
  • EUR 380.40
  • EUR 402.00
  • 100ul
  • 50ul
Description: A polyclonal antibody against CD163. Recognizes CD163 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IF; Recommended dilution: IF:1:50-1:200

Cd163 Antibody

1-CSB-PA650452LA01MO
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against Cd163. Recognizes Cd163 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB; Recommended dilution: WB:1:500-1:2000

CD163 Antibody

F50316-0.4ML 0.4 ml
EUR 322.15
Description: CD163 is an acute phase-regulated receptor involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. The protein may play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. It binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH-dependent manner. And it exhibits a higher affinity for complexes of hemoglobin and multimeric haptoglobin of HP*1F phenotype than for complexes of hemoglobin and dimeric haptoglobin of HP*1S phenotype. It also induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1.

CD163 Antibody

F50316-0.08ML 0.08 ml
EUR 140.25
Description: CD163 is an acute phase-regulated receptor involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. The protein may play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. It binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH-dependent manner. And it exhibits a higher affinity for complexes of hemoglobin and multimeric haptoglobin of HP*1F phenotype than for complexes of hemoglobin and dimeric haptoglobin of HP*1S phenotype. It also induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1.

CD163 Antibody

RQ4259 100 ug
EUR 356.15
Description: CD163 (Cluster of Differentiation 163) is a protein that in humans is encoded by the CD163 gene. The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

CD163 Antibody

R30973 100 ug
EUR 356.15
Description: CD163 (Cluster of Differentiation 163) is a human protein encoded by the CD163 gene. The receptor belongs to the scavenger receptor cysteine rich family type B and consists of an 1048 amino acid residues extracellular domain, a single transmembrane segment and a cytoplasmic tail with several splice variants. CD163 is a scavenger receptor for the hemoglobin-haptoglobincomplex. Using FISH, somatic cell hybrid analysis, and radiation hybrid analysis, Stover et al.(2000) mapped the CD163 gene to chromosome 12p13.3. Specific CD163-mediated endocytosis of haptoglobin-hemoglobin complexes was measurable in cells transfected with CD163 cDNA and in CD163-expressing myelomonocytic lymphoma cells.CD163 expression in monocytes promoted bacteria-induced proinflammatory cytokine production that could be blocked by anti-CD163 antibodies. Cells expressing human CD163 and recombinant protein containing the extracellular domain of CD163 supported adhesion of erythroblastic cells.

CD163 Antibody

R30974 100 ug
EUR 356.15
Description: Cluster of Differentiation 163, also known as Hemoglobin scavenger receptor, is a human protein encoded by the CD163 gene. The receptor belongs to the scavenger receptor cysteine rich family type B and consists of an 1048 amino acid residues extracellular domain, a single transmembrane segment and a cytoplasmic tail with several splice variants. CD163 is a scavenger receptorfor the hemoglobin-haptoglobin complex. Using FISH, somatic cell hybrid analysis, and radiation hybrid analysis, Stover et al.(2000) mapped the gene to chromosome 12p13.3. CD163 expression in monocytes promoted bacteria-induced proinflammatory cytokine production that could be blocked by CD163 antibody. Cells expressing human CD163 and recombinant protein containing the extracellular domain of CD163 supported adhesion of erythroblastic cells.

CD163 Antibody

V3937-100UG 100 ug
EUR 349.3
Description: This antibody recognizes a protein of 140kDa, identified as CD163. It has been identified as an acute phase-regulated transmembrane protein whose function is to mediate the endocytosis of haptoglobin-hemoglobin complexes. This receptor is expressed on the surface of monocytes with low expression and on tissue macrophages, histiocytes with high expression. Staining with anti-CD163 has been helpful to distinguish synovial macrophages from synovial intimal fibroblasts in rheumatoid arthritis, where its specificity for macrophages was found to be superior to that of anti-CD68. Increased levels of CD163 were also detected in patients with microbial infections and myelomonocytic leukemias. Anti-CD163 is of considerable value for selective identification of monocytes and macrophages at a certain stage of differentiation and is suitable for diagnosing myelomonocytic or monocytic leukaemia and neoplasms of true histiocytic origin. CD163 is positive in skin (histiocytes), gut, Kupffer cells, a few alveolar macrophages, macrophages in the placenta, and in macrophages in inflamed tissues including tumor tissue.

CD163 Antibody

V3937-20UG 20 ug
EUR 153.3
Description: This antibody recognizes a protein of 140kDa, identified as CD163. It has been identified as an acute phase-regulated transmembrane protein whose function is to mediate the endocytosis of haptoglobin-hemoglobin complexes. This receptor is expressed on the surface of monocytes with low expression and on tissue macrophages, histiocytes with high expression. Staining with anti-CD163 has been helpful to distinguish synovial macrophages from synovial intimal fibroblasts in rheumatoid arthritis, where its specificity for macrophages was found to be superior to that of anti-CD68. Increased levels of CD163 were also detected in patients with microbial infections and myelomonocytic leukemias. Anti-CD163 is of considerable value for selective identification of monocytes and macrophages at a certain stage of differentiation and is suitable for diagnosing myelomonocytic or monocytic leukaemia and neoplasms of true histiocytic origin. CD163 is positive in skin (histiocytes), gut, Kupffer cells, a few alveolar macrophages, macrophages in the placenta, and in macrophages in inflamed tissues including tumor tissue.

CD163 Antibody

V3937SAF-100UG 100 ug
EUR 349.3
Description: This antibody recognizes a protein of 140kDa, identified as CD163. It has been identified as an acute phase-regulated transmembrane protein whose function is to mediate the endocytosis of haptoglobin-hemoglobin complexes. This receptor is expressed on the surface of monocytes with low expression and on tissue macrophages, histiocytes with high expression. Staining with anti-CD163 has been helpful to distinguish synovial macrophages from synovial intimal fibroblasts in rheumatoid arthritis, where its specificity for macrophages was found to be superior to that of anti-CD68. Increased levels of CD163 were also detected in patients with microbial infections and myelomonocytic leukemias. Anti-CD163 is of considerable value for selective identification of monocytes and macrophages at a certain stage of differentiation and is suitable for diagnosing myelomonocytic or monocytic leukaemia and neoplasms of true histiocytic origin. CD163 is positive in skin (histiocytes), gut, Kupffer cells, a few alveolar macrophages, macrophages in the placenta, and in macrophages in inflamed tissues including tumor tissue.

CD163 Antibody

R20390-0.1ML 100ul
EUR 409

CD163 Antibody

V7470-100UG 100 ug
EUR 349.3
Description: This antibody recognizes a protein of 140kDa, identified as CD163. It has been identified as an acute phase-regulated transmembrane protein whose function is to mediate the endocytosis of haptoglobin-hemoglobin complexes. This receptor is expressed on the surface of monocytes with low expression and on tissue macrophages, histiocytes with high expression. Staining with anti-CD163 has been helpful to distinguish synovial macrophages from synovial intimal fibroblasts in rheumatoid arthritis, where its specificity for macrophages was found to be superior to that of anti-CD68. Increased levels of CD163 were also detected in patients with microbial infections and myelomonocytic leukemias. Anti-CD163 is of considerable value for selective identification of monocytes and macrophages at a certain stage of differentiation and is suitable for diagnosing myelomonocytic or monocytic leukaemia and neoplasms of true histiocytic origin. CD163 is positive in skin (histiocytes), gut, Kupffer cells, a few alveolar macrophages, macrophages in the placenta, and in macrophages in inflamed tissues including tumor tissue.

CD163 Antibody

V7470-20UG 20 ug
EUR 153.3
Description: This antibody recognizes a protein of 140kDa, identified as CD163. It has been identified as an acute phase-regulated transmembrane protein whose function is to mediate the endocytosis of haptoglobin-hemoglobin complexes. This receptor is expressed on the surface of monocytes with low expression and on tissue macrophages, histiocytes with high expression. Staining with anti-CD163 has been helpful to distinguish synovial macrophages from synovial intimal fibroblasts in rheumatoid arthritis, where its specificity for macrophages was found to be superior to that of anti-CD68. Increased levels of CD163 were also detected in patients with microbial infections and myelomonocytic leukemias. Anti-CD163 is of considerable value for selective identification of monocytes and macrophages at a certain stage of differentiation and is suitable for diagnosing myelomonocytic or monocytic leukaemia and neoplasms of true histiocytic origin. CD163 is positive in skin (histiocytes), gut, Kupffer cells, a few alveolar macrophages, macrophages in the placenta, and in macrophages in inflamed tissues including tumor tissue.

CD163 Antibody

V7470IHC-7ML 7 ml
EUR 349.3
Description: This antibody recognizes a protein of 140kDa, identified as CD163. It has been identified as an acute phase-regulated transmembrane protein whose function is to mediate the endocytosis of haptoglobin-hemoglobin complexes. This receptor is expressed on the surface of monocytes with low expression and on tissue macrophages, histiocytes with high expression. Staining with anti-CD163 has been helpful to distinguish synovial macrophages from synovial intimal fibroblasts in rheumatoid arthritis, where its specificity for macrophages was found to be superior to that of anti-CD68. Increased levels of CD163 were also detected in patients with microbial infections and myelomonocytic leukemias. Anti-CD163 is of considerable value for selective identification of monocytes and macrophages at a certain stage of differentiation and is suitable for diagnosing myelomonocytic or monocytic leukaemia and neoplasms of true histiocytic origin. CD163 is positive in skin (histiocytes), gut, Kupffer cells, a few alveolar macrophages, macrophages in the placenta, and in macrophages in inflamed tissues including tumor tissue.

CD163 Antibody

V7470SAF-100UG 100 ug
EUR 349.3
Description: This antibody recognizes a protein of 140kDa, identified as CD163. It has been identified as an acute phase-regulated transmembrane protein whose function is to mediate the endocytosis of haptoglobin-hemoglobin complexes. This receptor is expressed on the surface of monocytes with low expression and on tissue macrophages, histiocytes with high expression. Staining with anti-CD163 has been helpful to distinguish synovial macrophages from synovial intimal fibroblasts in rheumatoid arthritis, where its specificity for macrophages was found to be superior to that of anti-CD68. Increased levels of CD163 were also detected in patients with microbial infections and myelomonocytic leukemias. Anti-CD163 is of considerable value for selective identification of monocytes and macrophages at a certain stage of differentiation and is suitable for diagnosing myelomonocytic or monocytic leukaemia and neoplasms of true histiocytic origin. CD163 is positive in skin (histiocytes), gut, Kupffer cells, a few alveolar macrophages, macrophages in the placenta, and in macrophages in inflamed tissues including tumor tissue.

CD163 Antibody

V8227-100UG 100 ug
EUR 349.3
Description: This MAb recognizes a protein of 140kDa, identified as CD163. It has been identified as an acute phase-regulated transmembrane protein whose function is to mediate the endocytosis of haptoglobin-hemoglobin complexes. This receptor is expressed on the surface of monocytes with low expression and on tissue macrophages, histiocytes with high expression. Staining with anti-CD163 has been helpful to distinguish synovial macrophages from synovial intimal fibroblasts in rheumatoid arthritis, where its specificity for macrophages was found to be superior to that of anti-CD68. Increased levels of CD163 were also detected in patients with microbial infections and myelomonocytic leukemias. Anti-CD163 is of considerable value for selective identification of monocytes and macrophages at a certain stage of differentiation and is suitable for diagnosing myelomonocytic or monocytic leukaemia and neoplasms of true histiocytic origin. CD163 is positive in skin (histiocytes), gut, Kupffer cells, a few alveolar macrophages, macrophages in the placenta, and in macrophages in inflamed tissues including tumor tissue.

CD163 Antibody

V8227-20UG 20 ug
EUR 153.3
Description: This MAb recognizes a protein of 140kDa, identified as CD163. It has been identified as an acute phase-regulated transmembrane protein whose function is to mediate the endocytosis of haptoglobin-hemoglobin complexes. This receptor is expressed on the surface of monocytes with low expression and on tissue macrophages, histiocytes with high expression. Staining with anti-CD163 has been helpful to distinguish synovial macrophages from synovial intimal fibroblasts in rheumatoid arthritis, where its specificity for macrophages was found to be superior to that of anti-CD68. Increased levels of CD163 were also detected in patients with microbial infections and myelomonocytic leukemias. Anti-CD163 is of considerable value for selective identification of monocytes and macrophages at a certain stage of differentiation and is suitable for diagnosing myelomonocytic or monocytic leukaemia and neoplasms of true histiocytic origin. CD163 is positive in skin (histiocytes), gut, Kupffer cells, a few alveolar macrophages, macrophages in the placenta, and in macrophages in inflamed tissues including tumor tissue.

CD163 Antibody

V8227SAF-100UG 100 ug
EUR 349.3
Description: This MAb recognizes a protein of 140kDa, identified as CD163. It has been identified as an acute phase-regulated transmembrane protein whose function is to mediate the endocytosis of haptoglobin-hemoglobin complexes. This receptor is expressed on the surface of monocytes with low expression and on tissue macrophages, histiocytes with high expression. Staining with anti-CD163 has been helpful to distinguish synovial macrophages from synovial intimal fibroblasts in rheumatoid arthritis, where its specificity for macrophages was found to be superior to that of anti-CD68. Increased levels of CD163 were also detected in patients with microbial infections and myelomonocytic leukemias. Anti-CD163 is of considerable value for selective identification of monocytes and macrophages at a certain stage of differentiation and is suitable for diagnosing myelomonocytic or monocytic leukaemia and neoplasms of true histiocytic origin. CD163 is positive in skin (histiocytes), gut, Kupffer cells, a few alveolar macrophages, macrophages in the placenta, and in macrophages in inflamed tissues including tumor tissue.

CD163 Antibody

V8415-100UG 100 ug
EUR 349.3
Description: This MAb recognizes a protein of 140kDa, identified as CD163. It has been identified as an acute phase-regulated transmembrane protein whose function is to mediate the endocytosis of haptoglobin-hemoglobin complexes. This receptor is expressed on the surface of monocytes with low expression and on tissue macrophages, histiocytes with high expression. Staining with anti-CD163 has been helpful to distinguish synovial macrophages from synovial intimal fibroblasts in rheumatoid arthritis, where its specificity for macrophages was found to be superior to that of anti-CD68. Increased levels of CD163 were also detected in patients with microbial infections and myelomonocytic leukemias. Anti-CD163 is of considerable value for selective identification of monocytes and macrophages at a certain stage of differentiation and is suitable for diagnosing myelomonocytic or monocytic leukaemia and neoplasms of true histiocytic origin. CD163 is positive in skin (histiocytes), gut, Kupffer cells, a few alveolar macrophages, macrophages in the placenta, and in macrophages in inflamed tissues including tumor tissue.

CD163 Antibody

V8415-20UG 20 ug
EUR 153.3
Description: This MAb recognizes a protein of 140kDa, identified as CD163. It has been identified as an acute phase-regulated transmembrane protein whose function is to mediate the endocytosis of haptoglobin-hemoglobin complexes. This receptor is expressed on the surface of monocytes with low expression and on tissue macrophages, histiocytes with high expression. Staining with anti-CD163 has been helpful to distinguish synovial macrophages from synovial intimal fibroblasts in rheumatoid arthritis, where its specificity for macrophages was found to be superior to that of anti-CD68. Increased levels of CD163 were also detected in patients with microbial infections and myelomonocytic leukemias. Anti-CD163 is of considerable value for selective identification of monocytes and macrophages at a certain stage of differentiation and is suitable for diagnosing myelomonocytic or monocytic leukaemia and neoplasms of true histiocytic origin. CD163 is positive in skin (histiocytes), gut, Kupffer cells, a few alveolar macrophages, macrophages in the placenta, and in macrophages in inflamed tissues including tumor tissue.

CD163 Antibody

V8415SAF-100UG 100 ug
EUR 349.3
Description: This MAb recognizes a protein of 140kDa, identified as CD163. It has been identified as an acute phase-regulated transmembrane protein whose function is to mediate the endocytosis of haptoglobin-hemoglobin complexes. This receptor is expressed on the surface of monocytes with low expression and on tissue macrophages, histiocytes with high expression. Staining with anti-CD163 has been helpful to distinguish synovial macrophages from synovial intimal fibroblasts in rheumatoid arthritis, where its specificity for macrophages was found to be superior to that of anti-CD68. Increased levels of CD163 were also detected in patients with microbial infections and myelomonocytic leukemias. Anti-CD163 is of considerable value for selective identification of monocytes and macrophages at a certain stage of differentiation and is suitable for diagnosing myelomonocytic or monocytic leukaemia and neoplasms of true histiocytic origin. CD163 is positive in skin (histiocytes), gut, Kupffer cells, a few alveolar macrophages, macrophages in the placenta, and in macrophages in inflamed tissues including tumor tissue.

CD163 Antibody

V8757-100UG 100 ug
EUR 349.3
Description: CD163 is a type I membrane protein, and is a member of the hemoglobin scavenger receptor cystein-rich superfamily. The protein is involved in the clearance of hemoglobin-haptoglobin complexes and is considered to have anti-inflammatory functions. CD163 expression is restricted to the monocytic/macrophage lineage. It is expressed by all circulating monocytes and by a majority of tissue macrophages, such as splenic dendrocytes, alveolar macrophages and Kupffer cells of the liver. It is not present in macrophages in the mantle zone and some of the germinal center cells in lymph follicles, nor in Langerhans cells and interdigitating reticulum cells. In tumor tissues, CD163 is found in almost all cases of acute myeloid leukemia with monocytoid differentiation and in the majority of cases of histiocytic sarcoma, littoral cell angioma, Rosai-Dorfman disease, Langerhans cell histiocytosis and typical and atypical fibrous histiocytoma. It is also expressed in some cases of dermatofibrosarcoma protuberans. CD163 can be used to detect cells of monocytic and histiocyte lineage in neoplastic and reactive lesions. It has been shown to be more sensitive than CD68 for the detection of macrophages and monocytic cells. It covers a similar, but not identical, spectrum of cells as CD68.

CD163 Antibody

V8757-20UG 20 ug
EUR 153.3
Description: CD163 is a type I membrane protein, and is a member of the hemoglobin scavenger receptor cystein-rich superfamily. The protein is involved in the clearance of hemoglobin-haptoglobin complexes and is considered to have anti-inflammatory functions. CD163 expression is restricted to the monocytic/macrophage lineage. It is expressed by all circulating monocytes and by a majority of tissue macrophages, such as splenic dendrocytes, alveolar macrophages and Kupffer cells of the liver. It is not present in macrophages in the mantle zone and some of the germinal center cells in lymph follicles, nor in Langerhans cells and interdigitating reticulum cells. In tumor tissues, CD163 is found in almost all cases of acute myeloid leukemia with monocytoid differentiation and in the majority of cases of histiocytic sarcoma, littoral cell angioma, Rosai-Dorfman disease, Langerhans cell histiocytosis and typical and atypical fibrous histiocytoma. It is also expressed in some cases of dermatofibrosarcoma protuberans. CD163 can be used to detect cells of monocytic and histiocyte lineage in neoplastic and reactive lesions. It has been shown to be more sensitive than CD68 for the detection of macrophages and monocytic cells. It covers a similar, but not identical, spectrum of cells as CD68.